impurities
≤20 ppm heavy metals (verfied on random samples only)
ign. residue
≤3.0%
loss
≤5% loss on drying
pH
5.0-8.0 (15% in H2O)
viscosity
150-450 mPa.s, 20 % in solution(23 °C) (RVT, SP 2/100 RPM)
ester number
50‑115 mg KOH/g
suitability
complies for Infrared spectrum
Application
Kollicoat Protect is a ready-to-use moisture barrier system for use in combination with pigments. Kollicoat polymers can be employed as film coatings (intelligent surfaces) with controlled-release agents, for instant-release or sustained-release applications. Kollicoat polymers can be used with all standard coating equipment and are cost-effective, delivering maximum quality in terms of function, stability, and appearance. This research grade product is intended for use in R&D and development only.
Analysis Note
residual solvents (GLC-HS)
1,4 dioxane ≤380 ppm, ethylene glykol ≤620 ppm, vinyl acetate ≤100 ppm, methyl acetatea ≤1000 ppm, methanol ≤3000 ppm, acetic acid ≤15000 ppm
1,4 dioxane ≤380 ppm, ethylene glykol ≤620 ppm, vinyl acetate ≤100 ppm, methyl acetatea ≤1000 ppm, methanol ≤3000 ppm, acetic acid ≤15000 ppm
Legal Information
Kollicoat is a registered trademark of BASF SE
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
New insight into modified release pellets - Internal structure and drug release mechanism.
Ensslin S, Moll KP, Paulus K, Mader K.
J. Controlled Release, 128, 149-156 (2008)
Effect of water-soluble polymers on the physical stability of aqueous polymeric dispersions and their implications on the drug release from coated pellets.
Dashevsky A, Ahmed AR, et al.
Drug Devel. Ind. Pharm., 36, 152-160 (2010)
Sandra Strübing et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 66(1), 113-119 (2006-11-15)
The objective of this study was to receive detailed information on the mechanism of drug release from polyvinyl acetate (PVAc)/polyvinyl alcohol-polyethylene glycol graft copolymer (PVA-PEG) coated Propranolol HCl and Theophylline tablets. For this purpose the coating composition (PVAc/PVA-PEG: 90/10 and
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