40487
Sodium cis-homoaconitate tribasic
≥97.0% (HPLC)
别名:
(Z)-1-Butene-1,2,4-tricarboxylic acid trisodium salt, cis-Homoaconitic acid trisodium salt
方案
≥97.0% (HPLC)
表单
powder
杂质
≤10% water
SMILES字符串
[Na+].[Na+].[Na+].[O-]C(=O)CC\C(=C\C([O-])=O)C([O-])=O
InChI
1S/C7H8O6.3Na/c8-5(9)2-1-4(7(12)13)3-6(10)11;;;/h3H,1-2H2,(H,8,9)(H,10,11)(H,12,13);;;/q;3*+1/p-3/b4-3-;;;
InChI key
LQKFCFKBZKHIQH-FGSKAQBVSA-K
应用
Sodium cis-homoaconitate tribasic may be used as a substrate in studies of the biosynthesis of lysine in yeast.
生化/生理作用
cis-Homoaconitic acid is an intermediate in lysine biosynthesis, it is involved in the biosynthesis of coenzyme B in methanogenic Archaea.
包装
Bottomless glass bottle. Contents are inside inserted fused cone.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
此项目有
M E Maragoudakis
Journal of bacteriology, 94(4), 1060-1065 (1967-10-01)
Homoaconitic acid, the second intermediate of the proposed pathway for lysine biosynthesis in yeast, is accumulated in the growth medium of a lysine-requiring mutant. This acid has been identified on paper and column chromatography by comparing it with authentic cis-homoaconitic
Haruhito Tsutsui et al.
Journal of proteome research, 9(8), 3912-3922 (2010-06-19)
The number of diabetic patients has recently been increasing worldwide. Thus, the discovery of potential diabetic biomarker(s), leading to the early detection and/or prevention of diabetes mellitus, is strongly required. The diagnosis of the prediabetic state in humans is a
Enzymatic formation of cis-homoaconitic acid, an intermediate in lysine biosynthesis in yeast.
M Strassman et al.
The Journal of biological chemistry, 241(22), 5401-5407 (1966-11-25)
D M Howell et al.
Biochemistry, 37(28), 10108-10117 (1998-07-17)
The biochemistry of the 13 steps involved in the conversion of alpha-ketoglutarate and acetylCoA to alpha-ketosuberate, a precursor to the coenzymes coenzyme B (7-mercapto heptanoylthreonine phosphate) and biotin, has been established in Methanosarcina thermophila. These series of reactions begin with
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