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406OA-05A

Sigma-Aldrich

Human Osteoblasts-Osteoarthritis: HOb-OA, adult

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NACRES:
NA.81

生物来源

human bone (osteoarthritic)

质量水平

包装

pkg of 500,000 cells

manufacturer/tradename

Cell Applications, Inc

生长模式

Adherent

核型

2n = 46

形态学

osteoblast

technique(s)

cell culture | mammalian: suitable

相关疾病

arthritis

运输

dry ice

储存温度

−196°C

相关类别

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此商品
406RA-05A402OA-05A930-05A
packaging

pkg of 500,000 cells

packaging

pkg of 500,000 cells

packaging

pkg of 500,000 cells

packaging

pkg of 500,000 cells

growth mode

Adherent

growth mode

Adherent

growth mode

Adherent

growth mode

Adherent

karyotype

2n = 46

karyotype

2n = 46

karyotype

2n = 46

karyotype

-

morphology

osteoblast

morphology

osteoblast

morphology

chondrocyte

morphology

-

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

一般描述

Lot specific orders are not able to be placed through the web. Contact your local sales rep for more details.

Human Osteoblasts-Osteoarthritis, HOb-OA, are isolated from bone of patients with osteoarthritis (OA) and provide an excellent model system to study the patophisiology of that disease in vitro, including matrix mineralization, effects of inflammatory mediators and bone morphogenic proteins, physiological control of bone remodeling and regulation of bone metabolism.

Characterization: Positive for bone mineralization.

细胞系来源

Bone

应用

model system to study the pathophisiology of osteoarthritis, matrix mineralization, effects of inflammatory mediators, bone morphogenic proteins, bone remodeling and metabolism

组分

Basal Medium containing 10% FBS & 10% DMSO

制备说明

  • 2nd passage, >500,000 cells in Basal Medium containing 10% FBS & 10% DMSO
  • Can be cultured at least 10 doublings

传代培养常规

Please refer to the HOb-OA Culture Protocol.

免责声明

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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Xiangxiang Sun et al.
International journal of biological sciences, 16(6), 994-1009 (2020-03-07)
Osteoarthritis (OA) is a common type of arthritis. Chronic inflammation is an important contributor to the pathogenesis of OA. The maturation and secretion of proinflammatory cytokines are controlled by inflammasomes, especially NLRP1 (NLR Family Pyrin Domain Containing 1) and NLRP3.

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