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40809

嘌呤核苷磷酸化酶

Name: 嘌呤核苷磷酸化酶
Brand: SIGMA

recombinant, expressed in E. coli, ≥120 U/mL

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关于此项目

化学文摘社编号:

9030-21-1

UNSPSC Code:

12352204

EC 号:

2.4.2.1 (BRENDA, IUBMB)

MDL number:

MFCD00131739

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属性

recombinant

expressed in E. coli

form

buffered aqueous solution (100 mM phosphate buffer with 1 mM MgCl₂)

specific activity

≥120 U/mL

storage temp.

−20°C

InChI

1S/C10H12N4O4/c15-2-6-7(16)8(17)10(18-6)14-4-13-5-1-11-3-12-9(5)14/h1,3-4,6-8,10,15-17H,2H2/t6-,7-,8-,10-/m1/s1

InChI key

MRWXACSTFXYYMV-FDDDBJFASA-N

说明

Application

Purine nucleoside phosphorylase is used to study nucleotide salvage pathways and purine metabolism. It is used to study purine nucleoside phosphorylase deficiency and responsible PNP genetic mutations.

Biochem/physiol Actions

Purine nucleoside phosphorylase is an enzyme involved in purine metabolism. PNP metabolizes adenosine into adenine, inosine into hypoxanthine, and guanosine into guanine. Mutations in the PNP gene are responsible for purine nucleoside phosphorylase deficiency.

Other Notes

1 U will cause the phosphorolysis 1 μmol of inosine to hypoxanthine and ribose 1-phosphate per minute at pH 7.4 at 25°C

存储类别

12 - Non Combustible Liquids

怎么回事？

WGK 3

闪点 (F)

Not applicable

闪点 (°C)

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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