assay
≥98.0% (HPLC)
optical activity
[α]/D -65±3°, c = 1 in chloroform
mp
~258 °C (dec.)
application(s)
metabolomics
vitamins, nutraceuticals, and natural products
storage temp.
2-8°C
SMILES string
N21[C@@H](C[C@H]5[C@@H]([C@@H](OC=C5C(=O)OC)C)C2)c3[nH]c4c(c3CC1)cccc4
InChI
1S/C21H24N2O3/c1-12-16-10-23-8-7-14-13-5-3-4-6-18(13)22-20(14)19(23)9-15(16)17(11-26-12)21(24)25-2/h3-6,11-12,15-16,19,22H,7-10H2,1-2H3/t12-,15-,16+,19-/m0/s1
InChI key
GRTOGORTSDXSFK-XJTZBENFSA-N
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Application
Ajmalicine (δ-Yohimbine, Py-Tetrahydroserpentine, Raubasine) is an alkaloid used to study its effects as an antagonist of adrenergic and nicotinic receptors.
Biochem/physiol Actions
Metabolite in the indole alkaloid biosynthesis (serpentine production); found naturally in various plants such as Rauwolfia spp., Catharanthus roseus, and Mitragyna speciosa. It shows antimicrobial activity, and is used as an anti-hypertensive and sedative.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 2 Oral
存储类别
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
涉药品监管产品
此项目有
Roberts, M. F.
Alkaloids: biochemistry, ecology, and medicinal applications, 450-450 (1998)
David M Pereira et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 17(8-9), 646-652 (2009-12-08)
The leaves of Catharanthus roseus constitute the only source of the well known indolomonoterpenic alkaloids vincristine and vinblastine. In this work we studied the biological potential of the roots, which are used in several countries as decocts or hot water
Trends for diverse production strategies of plant medicinal alkaloids.
Liuqing Yang et al.
Natural product reports, 27(10), 1469-1479 (2010-08-24)
Catharanthus alkaloids and their enhanced production using elicitors: a review.
Gautam, S., et al.
International Journal of Pharmacy and Technology, 3, 713-724 (2011)
C Abdul Jaleel et al.
Colloids and surfaces. B, Biointerfaces, 62(1), 105-111 (2007-11-13)
In the present work, we have analysed the changes in the reactive oxygen metabolism of Catharanthus roseus (L.) G. Don. plants in terms of H(2)O(2) content, lipid peroxidation and the free radical quenching systems (non-enzymatic and enzymatic antioxidants) under drought
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 41111-10MG | 04061832071893 |
| 41111-50MG | 04061832071909 |
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