43381
(S)-Sodium 2,3-dihydroxyisovalerate hydrate
≥95.0% (CE)
别名:
(S)-2,3-Dihydroxy-3-methylbutanoic acid sodium salt, L(+)-α,β-Dihydroxyisovaleric acid sodium salt
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关于此项目
经验公式（希尔记法）:
C5H10O4
分子量:
134.13
PubChem Substance ID:
UNSPSC Code:
12352200
Beilstein/REAXYS Number:
4657323
MDL number:
Assay:
≥95.0% (CE)
Quality Level
assay
≥95.0% (CE)
optical purity
enantiomeric excess: ≥98.0%
storage temp.
2-8°C
SMILES string
O.[Na+].CC(C)(O)[C@H](O)C([O-])=O
InChI
1S/C5H10O4.Na.H2O/c1-5(2,9)3(6)4(7)8;;/h3,6,9H,1-2H3,(H,7,8);;1H2/q;+1;/p-1/t3-;;/m1../s1
InChI key
KGRRZNPTTZIUMS-HWYNEVGZSA-M
Application
Sodium 2,3-dihydroxyisovalerate hydrate may be used to study the distribution, function and kinetics of dihyroxy-acid dehydratases such as the superoxide-sensitive enzyme α, β-dihydroxyisovalerate dehydratase.
Biochem/physiol Actions
Metabolite in the pantothenate and CoA biosynthesis.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Eye Irrit. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
O R Brown et al.
Archives of biochemistry and biophysics, 319(1), 10-22 (1995-05-10)
Dihydroxy-acid dehydratase (DHAD) has a [4Fe-4S] cluster and is reported to be facilely inactivated by oxidant stress. To directly assess the biological effects in vivo of superoxide dismutase (SOD) on the oxidant sensitivity of DHAD, we used an Escherichia coli
Concepts and perspectives in enzyme stereochemistry.
K R Hanson
Annual review of biochemistry, 45, 307-330 (1976-01-01)
C F Kuo et al.
The Journal of biological chemistry, 262(10), 4724-4727 (1987-04-05)
Increasing the intracellular flux of O-2 by incubating aerobic Escherichia coli with paraquat or plumbagin markedly lowered the alpha, beta-dihydroxyisovalerate dehydratase activity detectable in extracts from these cells. This effect was not seen in the absence of dioxygen and was
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| 43381-10MG | 04061832404325 |