45480
麦角甾醇
≥95.0% (HPLC)
别名:
(3β)-麦角-5,7,22-三烯甘油-3-醇, 3β-羟基-5,7,22-麦角三烯, 维生素原 D2
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关于此项目
经验公式（希尔记法）:
C28H44O
化学文摘社编号:
分子量:
396.65
UNSPSC Code:
12352211
NACRES:
NA.79
PubChem Substance ID:
EC Number:
200-352-7
Beilstein/REAXYS Number:
2338604
MDL number:
InChI key
DNVPQKQSNYMLRS-APGDWVJJSA-N
InChI
1S/C28H44O/c1-18(2)19(3)7-8-20(4)24-11-12-25-23-10-9-21-17-22(29)13-15-27(21,5)26(23)14-16-28(24,25)6/h7-10,18-20,22,24-26,29H,11-17H2,1-6H3/b8-7+/t19-,20+,22-,24+,25-,26-,27-,28+/m0/s1
SMILES string
[H][C@@]1(CC[C@@]2([H])C3=CC=C4C[C@@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)[C@H](C)\C=C\[C@H](C)C(C)C
biological source
plant
assay
≥95.0% (HPLC)
form
powder or crystals
optical activity
[α]20/D −120±10°, c = 1% in chloroform
impurities
~3% water
color
white to faint yellow
mp
156-158 °C (lit.), 160-163 °C
functional group
hydroxyl
storage temp.
2-8°C
Quality Level
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Biochem/physiol Actions
麦角甾醇是维生素 D2 的生物前体，存在于真菌和一些原生生物如锥虫的细胞膜中。麦角甾醇可用于抗真菌药物如两性霉素 B 及其类似物的功能研究以及各种真菌中麦角甾醇生物合成途径的研究。
hcodes
pcodes
Hazard Classifications
Aquatic Chronic 4
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
Daniel S Palacios et al.
Proceedings of the National Academy of Sciences of the United States of America, 108(17), 6733-6738 (2011-03-04)
Amphotericin B is the archetype for small molecules that form transmembrane ion channels. However, despite extensive study for more than five decades, even the most basic features of this channel structure and its contributions to the antifungal activities of this
Ying-Yong Zhao et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 879(21), 1945-1953 (2011-06-15)
Rapid resolution liquid chromatography/tandem multi-stage mass spectrometry (RRLC-MS(n)) and rapid resolution liquid chromatography/tandem mass spectrometry (RRLC/MS/MS) methods were developed for the identification and quantification of ergosterol and its metabolites from rat plasma, urine and faeces. Two metabolites (ERG1 and ERG2)
Diego Morales et al.
Biotechnology progress, 34(3), 746-755 (2018-02-02)
Three extraction methods were sequentially combined to obtain fractions from Lentinula edodes (shiitake mushrooms) containing bioactive compounds against cardiovascular diseases (CVDs). Fruiting bodies were first extracted with plain water, obtained residue was then submitted to supercritical fluid extraction (SFE) and
Tamires A Bitencourt et al.
Frontiers in microbiology, 11, 193-193 (2020-03-11)
The ability of fungi to sense environmental stressors and appropriately respond is linked to secretory system functions. The dermatophyte infection process depends on an orchestrated signaling regulation that triggers the transcription of genes responsible for adherence and penetration of the
K E Clemmensen et al.
Science (New York, N.Y.), 339(6127), 1615-1618 (2013-03-30)
Boreal forest soils function as a terrestrial net sink in the global carbon cycle. The prevailing dogma has focused on aboveground plant litter as a principal source of soil organic matter. Using (14)C bomb-carbon modeling, we show that 50 to
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