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50214

Dy-677 NHS ester

Name: Dy-677 NHS ester
Brand: SIGMA

suitable for fluorescence

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关于此项目

经验公式（希尔记法）:

C₄₇H₄₉N₃Na₂O₁₄S₃

分子量:

1022.08

NACRES:

NA.32

PubChem Substance ID:

329757579

UNSPSC Code:

12352200

MDL number:

MFCD12912384

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属性

form

solid

fluorescence

λ_ex 666 nm; λ_em 700 nm in 0.1 M phosphate pH 7.0

suitability

corresponds for coupling to amines, suitable for fluorescence

storage temp.

2-8°C

SMILES string

[Na+].[Na+].CC1=CC(C)(C)N(CCCS([O-])(=O)=O)c2cc3[o+]c(cc(\C=C\C=C4/N(CCCS([O-])(=O)=O)c5ccc(cc5C4(C)CCCC(=O)ON6C(=O)CCC6=O)S([O-])(=O)=O)c3cc12)-c7ccccc7

InChI

1S/C47H51N3O14S3.2Na/c1-31-30-46(2,3)49(23-11-25-66(57,58)59)39-29-41-36(28-35(31)39)33(26-40(63-41)32-12-6-5-7-13-32)14-8-15-42-47(4,21-9-16-45(53)64-50-43(51)19-20-44(50)52)37-27-34(67(60,61)62)17-18-38(37)48(42)22-10-24-65(54,55)56;;/h5-8,12-15,17-18,26-30H,9-11,16,19-25H2,1-4H3,(H2-,54,55,56,57,58,59,60,61,62);;/q;2*+1/p-2/b14-8+,42-15-;;

InChI key

ZCQYZZOGJZASLR-MNBUABMSSA-L

说明

Application

Dy-677 NHS ester, an amine coupling asymmetric cyanine reagent, is used for fluorescent labeling of amine groups within proteins, amino derivatized oligonucleotide and other amine containing molecules.

存储类别

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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分析证书(COA)

Lot/Batch Number

1399612

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Traceable multifunctional micellar nanocarriers for cancer-targeted co-delivery of MDR-1 siRNA and doxorubicin.

Xiao-Bing Xiong et al.

ACS nano, 5(6), 5202-5213 (2011-06-02)

In this article we report on the development of polymeric micelles that can integrate multiple functions in one system, including the capability to accommodate a combination of therapeutic entities with different physicochemical properties (i.e., siRNA and doxorubicin; DOX), passive and

Suitable labels for molecular imaging--influence of dye structure and hydrophilicity on the spectroscopic properties of IgG conjugates.

Jutta Pauli et al.

Bioconjugate chemistry, 22(7), 1298-1308 (2011-05-19)

Aiming at the design of highly brilliant NIR emissive optical probes, e.g., for in vivo near-infrared fluorescence imaging (NIRF), we studied the absorption and fluorescence properties of the asymmetric cyanines Dy678, Dy681, Dy682, and Dy676 conjugated to the model antibody

Controlled modulation of serum protein binding and biodistribution of asymmetric cyanine dyes by variation of the number of sulfonate groups.

Franziska M Hamann et al.

Molecular imaging, 10(4), 258-269 (2011-04-28)

To assess the suitability of asymmetric cyanine dyes for in vivo fluoro-optical molecular imaging, a comprehensive study on the influence of the number of negatively charged sulfonate groups governing the hydrophilicity of the DY-67x family of asymmetric cyanines was performed.

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货号	GTIN
50214-1MG	04061826588390