51455
维生素 K3 2,3-环氧
≥98.5% (HPLC)
别名:
1a，7a-二氢-1a-甲基萘[2，3-b] 环氧乙烯-2，7-二酮, 2-甲基-1，4-萘醌环氧化物, 2，3-环氧-2，3-二氢-2-甲基-1，4-萘醌, 甲萘醌2，3-环氧化物, 神经干细胞 65669
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关于此项目
经验公式（希尔记法）:
C11H8O3
化学文摘社编号:
分子量:
188.18
PubChem Substance ID:
UNSPSC Code:
12352200
Beilstein/REAXYS Number:
144630
MDL number:
产品名称
维生素 K3 2,3-环氧, ≥98.5% (HPLC)
SMILES string
O=C1C2(C)C(O2)C(C3=CC=CC=C31)=O
InChI
1S/C11H8O3/c1-11-9(13)7-5-3-2-4-6(7)8(12)10(11)14-11/h2-5,10H,1H3
InChI key
NNUKDUBCRRYXDC-UHFFFAOYSA-N
assay
≥98.5% (HPLC)
form
powder
color
white
suitability
complies for H-NMR
application(s)
cell analysis
storage temp.
−20°C
Biochem/physiol Actions
维生素K代谢的代谢产物。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Xiao Lu et al.
ACS medicinal chemistry letters, 3(12), 1029-1033 (2012-12-13)
Cations of hydroxy-substituted 1,4-naphthoquinones were synthesized and evaluated as antiplasmodial agents against Plasmodium falciparum. The atovaquone analogues were found to be inactive as antagonists of parasite growth, which was attributed to ionization of the acidic hydroxyl moiety. Upon modification to
Syed Masood Husain et al.
Angewandte Chemie (International ed. in English), 53(37), 9806-9811 (2014-07-23)
Quinones and hydroquinones are among the most common cellular cofactors, redox mediators, and natural products. Here, we report on the reduction of 2-hydroxynaphthoquinones to the stable 1,4-diketo tautomeric form of hydronaphthoquinones and their further reduction by fungal tetrahydroxynaphthalene reductase. The
Nan Chen et al.
Organic letters, 10(3), 381-384 (2008-01-11)
An efficient three-step construction of the highly oxygenated D-ring of the kinamycin antibiotics is reported for a simple model system. A comparison of the spectroscopic characteristics of the synthetic models with those of natural kinamycin F, which is suspected to
Toru Kitano et al.
Biological & pharmaceutical bulletin, 35(4), 617-623 (2012-04-03)
We investigated the cytotoxicity of eight vitamin K3 (VK3) analogs against neuroblastoma cell lines (IMR-32, LA-N-1, NB-39, and SK-N-SH) and normal cell lines (human umbilical vein endothelial cells (HUVEC) and human dermal fibroblasts (HDF)) using a 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide (MTT) assay.
Synthesis, thiol-mediated reactive oxygen species generation profiles and anti-proliferative activities of 2,3-epoxy-1,4-naphthoquinones.
Dharmaraja, A.T., et al
MedChemComm, 3, 219-224 (2012)
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