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Merck
CN

51511

L -3-氨基丁酸

≥97.0% (TLC)

别名:

(+)-β-氨基异丁酸, (2S)-3-氨基-2-甲基丙酸, (S)-β-AIB, (S)-β2-高丙氨酸, (S)-3-氨基-2-甲基丙酸, L-α-甲基-β-丙氨酸, S-BAIBA

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关于此项目

经验公式(希尔记法):
C4H9NO2
化学文摘社编号:
分子量:
103.12
UNSPSC Code:
12352209
PubChem Substance ID:
MDL number:
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InChI

1S/C4H9NO2/c1-3(2-5)4(6)7/h3H,2,5H2,1H3,(H,6,7)/t3-/m0/s1

SMILES string

C[C@@H](CN)C(O)=O

InChI key

QCHPKSFMDHPSNR-VKHMYHEASA-N

assay

≥97.0% (TLC)

optical activity

[α]/D -15.0±2.0°, c = 0.1 in H2O

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Biochem/physiol Actions

beta-Aminoisobutyric acid (BAIBA) is a metabolic biomarker for body exercise induced white fat burning. BAIBA levels rise during exercise and are inversely associated with metabolic risk factors. Specifically, BAIBA levels were inversely correlated with fasting blood sugar levels, insulin, triglycerides, and total cholesterol. The findings suggest that BAIBA may contribute to exercise-induced protection from metabolic diseases.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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分析证书(COA)

Lot/Batch Number

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J J Slon-Usakiewicz et al.
Biochemistry, 36(44), 13494-13502 (1997-11-14)
We have designed bivalent thrombin inhibitors, consisting of a nonsubstrate type active site blocking segment, a hirudin-based fibrinogen recognition exosite blocking segment, and a linker connecting these segments. The inhibition provided by the bivalent inhibitors with various linker lengths revealed
S Ueno et al.
Biochimica et biophysica acta, 1033(2), 169-175 (1990-02-26)
D-3-Aminoisobutyrate-pyruvate aminotransferase (EC 2.6.1.40) was purified 1900-fold from rat liver extract. The purified enzyme showed a molecular mass of 180 kDa by gel-permeation HPLC analysis using a TSK gel G3000SW column. Reductive polyacrylamide gel electrophoresis in sodium dodecyl sulfate resulted
Chunyan Wang et al.
Amino acids, 44(2), 661-671 (2012-08-31)
The quantitative analysis of amino acids (AAs) in single dry blood spot (DBS) samples is an important issue for metabolic diseases as a second-tier test in newborn screening. An analytical method for quantifying underivatized AAs in DBS was developed by
Structures, semisyntheses, and absolute configurations of the antiplasmodial α-substituted β-lactam monamphilectines B and C from the sponge Svenzea flava.
Aviles, E., et al.
Tetrahedron, 71, 487-494 (2015)
C R Roe et al.
Molecular genetics and metabolism, 65(1), 35-43 (1998-10-27)
A patient presenting with developmental delay but no episodes of metabolic acidosis was found to excrete significant amounts of methylmalonate (MMA) without any associated increased excretion of malonate, ethylmalonate, 3-hydroxypropionate, or beta-alanine. In contrast to patients with methylmalonic aciduria due

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