51511
L -3-氨基丁酸
≥97.0% (TLC)
别名:
(+)-β-氨基异丁酸, (2S)-3-氨基-2-甲基丙酸, (S)-β-AIB, (S)-β2-高丙氨酸, (S)-3-氨基-2-甲基丙酸, L-α-甲基-β-丙氨酸, S-BAIBA
方案
≥97.0% (TLC)
旋光性
[α]/D -15.0±2.0°, c = 0.1 in H2O
SMILES字符串
C[C@@H](CN)C(O)=O
InChI
1S/C4H9NO2/c1-3(2-5)4(6)7/h3H,2,5H2,1H3,(H,6,7)/t3-/m0/s1
InChI key
QCHPKSFMDHPSNR-VKHMYHEASA-N
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生化/生理作用
beta-Aminoisobutyric acid (BAIBA) is a metabolic biomarker for body exercise induced white fat burning. BAIBA levels rise during exercise and are inversely associated with metabolic risk factors. Specifically, BAIBA levels were inversely correlated with fasting blood sugar levels, insulin, triglycerides, and total cholesterol. The findings suggest that BAIBA may contribute to exercise-induced protection from metabolic diseases.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
此项目有
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The quantitative analysis of amino acids (AAs) in single dry blood spot (DBS) samples is an important issue for metabolic diseases as a second-tier test in newborn screening. An analytical method for quantifying underivatized AAs in DBS was developed by
S Ueno et al.
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D-3-Aminoisobutyrate-pyruvate aminotransferase (EC 2.6.1.40) was purified 1900-fold from rat liver extract. The purified enzyme showed a molecular mass of 180 kDa by gel-permeation HPLC analysis using a TSK gel G3000SW column. Reductive polyacrylamide gel electrophoresis in sodium dodecyl sulfate resulted
C R Roe et al.
Molecular genetics and metabolism, 65(1), 35-43 (1998-10-27)
A patient presenting with developmental delay but no episodes of metabolic acidosis was found to excrete significant amounts of methylmalonate (MMA) without any associated increased excretion of malonate, ethylmalonate, 3-hydroxypropionate, or beta-alanine. In contrast to patients with methylmalonic aciduria due
J J Slon-Usakiewicz et al.
Biochemistry, 36(44), 13494-13502 (1997-11-14)
We have designed bivalent thrombin inhibitors, consisting of a nonsubstrate type active site blocking segment, a hirudin-based fibrinogen recognition exosite blocking segment, and a linker connecting these segments. The inhibition provided by the bivalent inhibitors with various linker lengths revealed
Structures, semisyntheses, and absolute configurations of the antiplasmodial α-substituted β-lactam monamphilectines B and C from the sponge Svenzea flava.
Aviles, E., et al.
Tetrahedron, 71, 487-494 (2015)
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