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Merck
CN

54298

(−)-Nortrachelogenin

≥95.0% (HPLC)

别名:

(−)-Wikstromol, (3S)-4,5-Dihydro-4β-(4-hydroxy-3-methoxybenzyl)-3-(4-hydroxy-3-methoxybenzyl)-3β-hydroxyfuran-2(3H)-one, (3S,4S)-3-Hydroxy-3,4-bis(4-hydroxy-3-methoxybenzyl)dihydrofuran-2-one, (3S,4S)-Dihydro-3-hydroxy-3,4-bis[(4-hydroxy-3-methoxyphenyl)methyl]-2(3H)-furanone, NSC 271296, Pinopalustrin

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关于此项目

经验公式(希尔记法):
C20H22O7
化学文摘社编号:
分子量:
374.38
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
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InChI

1S/C20H22O7/c1-25-17-8-12(3-5-15(17)21)7-14-11-27-19(23)20(14,24)10-13-4-6-16(22)18(9-13)26-2/h3-6,8-9,14,21-22,24H,7,10-11H2,1-2H3/t14-,20-/m0/s1

SMILES string

COc1cc(C[C@H]2COC(=O)[C@]2(O)Cc3ccc(O)c(OC)c3)ccc1O

InChI key

ZITBJWXLODLDRH-XOBRGWDASA-N

assay

≥95.0% (HPLC)

Application

Nortrachelogenin [(−)-Wikstromol], a bioactive α-hydroxylated lactone, is a pharmacologically active lignan used to study its antitumor activities versus breast and lung cancer cells. Nortrachelogenin may be used as a reference compound during the isolation and identification of α-hydroxylated lactone type lignans.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

pictograms

Environment

signalword

Warning

hcodes

pcodes

Hazard Classifications

Aquatic Acute 1

存储类别

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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历史批次信息供参考:

分析证书(COA)

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Ruchira Wangteeraprasert et al.
Phytotherapy research : PTR, 26(10), 1496-1499 (2012-02-07)
In our continuing efforts to find new antiherpetic agents from plants, an extract prepared from the stems of Carissa spinarum L. was found to possess appreciable activity against herpes simplex viruses (HSV I and II). A chemical study of this
Plant anticancer agents XXXIII. Constituents of Passerina vulgaris.
J X Guo et al.
Planta medica, 50(3), 264-265 (1984-06-01)
Xing-Qi Tan et al.
Planta medica, 71(1), 93-95 (2005-01-29)
Seven lignans having a diarylhydroxybutyrolactone skeleton were isolated from the leaves and stems of Trachelospermum jasminoides (Lindl.) Lem. Their structures were elucidated to be nortrachelogenin 8' -O-beta-D-glucopyranoside (1), nortrachelogenin 5'- C- beta-D-glucopyranoside (2), trachelogenin amide (3), nortracheloside, trachelogenin, tracheloside, and
A K Tiwari et al.
Journal of agricultural and food chemistry, 49(10), 4642-4645 (2001-10-16)
An activity-directed fractionation and purification process was used to identify the antioxidant components of Cedrus deodara. Dried heartwood powder of C. deodara was first defatted with petroleum ether and then extracted with chloroform. The chloroform extract showed strong antioxidant activity
Wei-sheng Feng et al.
Yao xue xue bao = Acta pharmaceutica Sinica, 38(12), 927-930 (2004-03-26)
To study the chemical constituents from the water-extracts of pine needles of Pinus massoniana Lamb. Chromatographic techniques were used to separate and purify compounds. Their physico-chemical properties and spectral data (UV, IR, MS, 1H-1H, 13C-1H NMR, DEPT, HMBC etc.) were

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