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Merck
CN

55627

7-Hydroxy-4-methyl-2(1H)-quinolone

suitable for fluorescence, ≥97.0% (HPLC)

别名:

7-Hydroxy-4-methylcarbostyryl, 2,7-Dihydroxy-4-methylquinoline

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关于此项目

经验公式(希尔记法):
C10H9NO2
化学文摘社编号:
分子量:
175.18
UNSPSC Code:
12352202
NACRES:
NA.32
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1528280
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InChI

1S/C10H9NO2/c1-6-4-10(13)11-9-5-7(12)2-3-8(6)9/h2-5,12H,1H3,(H,11,13)

SMILES string

Cc1cc(O)nc2cc(O)ccc12

InChI key

MYEVEFULPUKTSZ-UHFFFAOYSA-N

assay

≥97.0% (HPLC)

form

solid

mp

≥250 °C (lit.)

solubility

DMF: soluble, DMSO: soluble, alcohols: soluble

fluorescence

λex 321 nm; λem 357 nm (pH 5.0), λex 351 nm; λem 428 nm in 0.1 M Tris pH 9.0

suitability

suitable for fluorescence

Application

7-Hydroxy-4-methyl-2(1H)-quinolone may be used as a reference material in the study and analysis of quinolone derivatives in research areas such as carcinogenicity and quinolone metabolism.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

法规信息

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分析证书(COA)

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E J La Voie et al.
Carcinogenesis, 4(9), 1169-1173 (1983-09-01)
Quinoline is a hepatocarcinogen in mice and rats, a mutagen in Salmonella typhimurium, and induces unscheduled DNA synthesis in primary cultures of rat hepatocytes. In contrast, isoquinoline has not been shown to be genotoxic. The metabolites of quinoline and isoquinoline
A Rüger et al.
Biological chemistry Hoppe-Seyler, 374(7), 479-488 (1993-07-01)
A bacterial strain, designated K1, which utilizes 4-methylquinoline and quinoline as sole source of carbon, nitrogen and energy was isolated from soil. Based on its morphological and physiological characteristics, it was classified as Pseudomonas putida biovar B. Four metabolites of

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