Merck
CN

64951

Sigma-Aldrich

7-甲氧基香豆素

suitable for fluorescence, ≥98.0% (TLC)

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别名:
Methyl umbelliferyl ether, 赫尼亚林
Empirical Formula (Hill Notation):
C10H8O3
CAS号:
分子量:
176.17
Beilstein:
141728
EC 号:
MDL编号:
PubChem化学物质编号:
NACRES:
NA.32

质量水平

检测方案

≥98.0% (TLC)

形式

solid

mp

117-121 °C (lit.)

溶解性

DMF: soluble
acetonitrile: soluble
alcohols: soluble
chloroform: soluble

荧光

λex 350 nm; λem 385 nm (Reaction product)
λex 350 nm; λem 385 nm in chloroform

适用性

suitable for fluorescence

SMILES string

COc1ccc2C=CC(=O)Oc2c1

InChI

1S/C10H8O3/c1-12-8-4-2-7-3-5-10(11)13-9(7)6-8/h2-6H,1H3

InChI key

LIIALPBMIOVAHH-UHFFFAOYSA-N

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此商品
W515809254886PHL89733
7-Methoxycoumarin suitable for fluorescence, ≥98.0% (TLC)

Sigma-Aldrich

64951

7-甲氧基香豆素

7-Methoxycoumarin ≥98%

Sigma-Aldrich

W515809

7-甲氧基香豆素

6,7-Dimethoxycoumarin 98%

Sigma-Aldrich

254886

6,7-二甲氧基香豆素

7-Methoxycoumarin phyproof® Reference Substance

PHL89733

7-甲氧基香豆素

mp

117-121 °C (lit.)

mp

115-121 °C, 117-121 °C (lit.)

mp

143-145 °C (lit.)

mp

117-121 °C (lit.)

form

solid

form

-

form

powder

form

crystals

solubility

DMF: soluble

solubility

-

solubility

-

solubility

-

fluorescence

λex 350 nm; λem 385 nm (Reaction product)

fluorescence

-

fluorescence

-

fluorescence

-

suitability

suitable for fluorescence

suitability

-

suitability

-

suitability

-

应用

7-Methoxycoumarin (Herniarin) is used to study antioxidant and hepatoprotective properties and its activity as an allergen. 7-Methoxycoumarin may be used as a reference material in the purification, separation and analysis of coumarin compounds.

储存分类代码

11 - Combustible Solids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


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Sigma-Aldrich

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7-羟基香豆素-3-羧酸

Scopoletin ≥99%

Sigma-Aldrich

S2500

东莨菪内酯

Sandesh Sancheti et al.
Drug and chemical toxicology, 36(1), 42-47 (2012-11-07)
The available conventional remedies for the treatment of drug-induced liver diseases are highly inadequate and possess serious adverse effects; therefore, the development of new, effective drugs is considered necessary. This article explores the hepatoprotective and antioxidant potential of 7-methylcoumarin (MC)
Chao-Mei Ma et al.
Phytochemical analysis : PCA, 18(1), 42-49 (2007-01-31)
A simple HPLC-PAD-MS method was established to quantitatively analyse two spiroether isomers (cis-en-yn-dicycloether and trans-en-yn-dicycloether) and the main coumarin, herniarin, in chamomile herbs, simultaneously. By using this method, the contents of these three compounds in the flowers of two chamomile
P Paterson et al.
Xenobiotica; the fate of foreign compounds in biological systems, 14(11), 849-859 (1984-11-01)
Pretreatment of rats with phenobarbitone increased hepatic microsomal 7-methoxy-and 7-ethoxy-coumarin O-dealkylase activities. Pretreatment with beta-naphthoflavone increased only the 7-ethoxycoumarin O-dealkylase activity. The addition of metyrapone in vitro inhibited the O-dealkylations to different extents. Similar results were obtained with diphenyloxazole and
Adriana Eliasová et al.
Zeitschrift fur Naturforschung. C, Journal of biosciences, 59(7-8), 543-548 (2005-04-09)
The responses of young plants of diploid and tetraploid Matricaria chamomilla cultivars to abiotic stress were studied. The course of quantitative changes of main leaf secondary metabolites was evaluated within an interval from 6 h before to 54 h after
M Warren et al.
Xenobiotica; the fate of foreign compounds in biological systems, 18(8), 973-981 (1988-08-01)
1. The activities of 7-methoxycoumarin (7-MCOD), 7-ethoxycoumarin (7-ECOD) and 7-propoxycoumarin (7-PCOD) O-dealkylases decreased by 75-90% during culture of rat hepatocytes for 72 h. 2. The addition of dexamethasone (D) produced a stabilization or modest enhancement of 7-ECOD and 7-PCOD activities

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