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Merck
CN

65906

鬼笔环肽–Atto 647N

BioReagent, suitable for fluorescence, ≥80% (HPLC)

别名:

Atto 647N, Atto 647N-鬼笔环肽

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关于此项目

NACRES:
NA.32
UNSPSC Code:
12171501
Manufacturer/tradename:
ATTO-TEC GmbH
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产品名称

鬼笔环肽–Atto 647N, BioReagent, suitable for fluorescence, ≥80% (HPLC)

Quality Level

product line

BioReagent

assay

≥80% (HPLC)

manufacturer/tradename

ATTO-TEC GmbH

λ

in methanol

UV absorption

λ: 640-646 nm Amax

suitability

suitable for fluorescence

detection method

fluorometric

storage temp.

−20°C

Application

Phalloidin–Atto 647Nis,设计用于标记 DNA、RNA 或蛋白质。phaloidin 的荧光结合物用于标记肌动蛋白丝,用于组织学应用。鬼笔环肽的某些结构特征是与肌动蛋白结合所必需的。

Features and Benefits

Atto 488-鬼笔环肽的特点:
  1. 强吸光度:
  2. 高荧光量子产率。
  3. 高光稳定性。
  4. 最低三重态。
  5. 好溶解性。
  6. 出色的抗臭氧性能。

General description

Phalloidin–Atto 647N 是一种新的荧光标记物,靶向红色光谱区域。Atto 647N 是一种阳离子染料,在耦合后,它携带 +1 的净电荷。与大多数 Atto 标签一样,Atto 647N 的吸收和荧光与 2-11 之间的 pH 无关。Atto 647N 是以含有两种具有相同荧光和吸收特性的异构体的混合物的形式提供的。Atto 标记物具有刚性结构,不显示任何顺反异构化。

Legal Information

本品仅供研究使用。如果打算商业化,请联系知识产权持有者(德国ATTO-TEC GmbH公司)申请许可。

pictograms

Skull and crossbones

signalword

Danger

Hazard Classifications

Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral

存储类别

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

法规信息

高风险级别生物产品--毒素类产品
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Georgios Trichas et al.
BMC biology, 6, 40-40 (2008-09-17)
Transgenic animals are widely used in biomedical research and biotechnology. Multicistronic constructs, in which several proteins are encoded by a single messenger RNA, are commonly used in genetically engineered animals. This is currently done by using an internal ribosomal entry
Catherine Pfefferli et al.
Nature communications, 8, 15151-15151 (2017-05-04)
The existence of common mechanisms regulating organ regeneration is an intriguing concept. Here we report on a regulatory element that is transiently activated during heart and fin regeneration in zebrafish. This element contains a ctgfa upstream sequence, called careg, which
Benedetta Artegiani et al.
Nature cell biology, 22(3), 321-331 (2020-03-04)
CRISPR-Cas9 technology has revolutionized genome editing and is applicable to the organoid field. However, precise integration of exogenous DNA sequences into human organoids is lacking robust knock-in approaches. Here, we describe CRISPR-Cas9-mediated homology-independent organoid transgenesis (CRISPR-HOT), which enables efficient generation
Ceniz Zihni et al.
Nature cell biology, 19(9), 1049-1060 (2017-08-22)
Polarized epithelia develop distinct cell surface domains, with the apical membrane acquiring characteristic morphological features such as microvilli. Cell polarization is driven by polarity determinants including the evolutionarily conserved partitioning-defective (PAR) proteins that are separated into distinct cortical domains. PAR
Francesca Farina et al.
The EMBO journal, 38(11) (2019-04-25)
Cells going through mitosis undergo precisely timed changes in cell shape and organisation, which serve to ensure the fair partitioning of cellular components into the two daughter cells. These structural changes are driven by changes in actin filament and microtubule

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