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Merck
CN

68264

α-羟基异丁腈 β- D -吡喃葡萄糖苷

≥97% (HPLC)

别名:

α-羟基异丁腈 β- D -葡萄糖, 2-(β- D -吡喃葡萄糖氧基)-2-甲基丙腈, 亚麻苦苷

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关于此项目

经验公式(希尔记法):
C10H17NO6
化学文摘社编号:
分子量:
247.25
MDL编号:
UNSPSC代码:
12352201
PubChem化学物质编号:
NACRES:
NA.25
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生物来源

synthetic

质量水平

方案

≥97% (HPLC)

表单

solid

旋光性

[α]/D -26.5±2.0°, c = 1 in H2O

技术

HPLC: suitable

颜色

white to off-white

储存温度

2-8°C

SMILES字符串

CC(C)(O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)C#N

InChI

1S/C10H17NO6/c1-10(2,4-11)17-9-8(15)7(14)6(13)5(3-12)16-9/h5-9,12-15H,3H2,1-2H3/t5-,6-,7+,8-,9+/m1/s1

InChI key

QLTCHMYAEJEXBT-ZEBDFXRSSA-N

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应用

亚麻苦甙是一种氰基葡萄糖底物,与 β-葡糖苷酶、亚麻苦苷酶一起使用,在体内生成氰化物,作为潜在的抗癌策略。

生化/生理作用

木薯、利马豆、亚麻等植物的叶子和根中都含有的一种氰甙亚麻酸。蒙花苷及其甲基化的亲缘香豆素在人体肠道内酶和肠道菌群的作用下,可分解为有毒的氰化氢

包装

无底玻璃瓶。内含物装在插入的融合锥内。

其他说明

为了全面了解我们针对客户研究提供的各种单糖产品,建议您访问我们的碳水化合物分类页面。

象形图

Exclamation mark

警示用语:

Warning

危险分类

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Karin Forslund et al.
Plant physiology, 135(1), 71-84 (2004-05-04)
Lotus japonicus was shown to contain the two nitrile glucosides rhodiocyanoside A and rhodiocyanoside D as well as the cyanogenic glucosides linamarin and lotaustralin. The content of cyanogenic and nitrile glucosides in L. japonicus depends on plant developmental stage and
Vega García-Escudero et al.
Autophagy, 4(7), 923-925 (2008-08-22)
The understanding of the mechanisms of cell-death execution and the role that they play in different diseases opens new therapeutic strategies. Currently, increasing evidence indicates that autophagy is a frequent cell-death mechanism, so the question arises: Could autophagy stimulation be
Kirsten Jørgensen et al.
Plant physiology, 155(1), 282-292 (2010-11-04)
Cassava (Manihot esculenta) is a eudicotyledonous plant that produces the valine- and isoleucine-derived cyanogenic glucosides linamarin and lotaustralin with the corresponding oximes and cyanohydrins as key intermediates. CYP79 enzymes catalyzing amino acid-to-oxime conversion in cyanogenic glucoside biosynthesis are known from
Christine Männel-Croisé et al.
Analytical chemistry, 81(22), 9493-9498 (2009-10-22)
Corrin-based chemosensors allow the rapid and selective colorimetric detection of endogenous biological cyanide. The color change from orange to violet can be easily observed with the "naked eye" (Deltalambda(max) = 51 nm). The methodology works directly in the biological matrix
Eduardo Rivadeneyra-Domínguez et al.
Toxins, 12(11) (2020-11-14)
Cassava (Manihot esculenta Crantz) is a plant that contains neurotoxins such as linamarin and lotaustraline. Its long-term consumption is associated with neuronal damage and contributes to the development of motor impairment in humans and rats. We investigated the effects of

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