73248
醋酸美伦孕酮
≥97.0% (HPLC)
别名:
17α-乙酰氧基-6-甲基-16-亚甲基-4,6-孕甾二烯-3,20-二酮
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关于此项目
经验公式（希尔记法）:
C25H32O4
化学文摘社编号:
分子量:
396.52
PubChem Substance ID:
EC Number:
220-859-7
UNSPSC Code:
12352200
Beilstein/REAXYS Number:
2066919
MDL number:
InChI key
UDKABVSQKJNZBH-DWNQPYOZSA-N
InChI
1S/C25H32O4/c1-14-11-19-20(23(5)9-7-18(28)13-21(14)23)8-10-24(6)22(19)12-15(2)25(24,16(3)26)29-17(4)27/h11,13,19-20,22H,2,7-10,12H2,1,3-6H3/t19-,20+,22+,23-,24+,25+/m1/s1
SMILES string
[H][C@]12CC[C@@]3(C)[C@@]([H])(CC(=C)[C@]3(OC(C)=O)C(C)=O)[C@]1([H])C=C(C)C4=CC(=O)CC[C@]24C
assay
≥97.0% (HPLC)
form
solid
mp
202-204 °C (lit.)
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Biochem/physiol Actions
Causes shrinkage of androgen-dependent prostate tumors.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
signalword
Warning
hcodes
Hazard Classifications
Repr. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
ppe
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
法规信息
涉药品监管产品
此项目有
G M Padilla et al.
Biochemistry and cell biology = Biochimie et biologie cellulaire, 68(10), 1181-1188 (1990-10-01)
We had previously reported that 6-methylene progesterone, an inhibitor of 5 alpha-reductase, the enzyme which converts testosterone to dihydrotestosterone, markedly inhibited growth of the androgen-dependent Dunning R3327-H rat prostatic tumors. We now find that the progesterone derivatives melengestrol acetate (MGA)
Brett J Theeler et al.
Journal of the neurological sciences, 353(1-2), 92-97 (2015-05-03)
Brainstem gliomas are rare in adults and overall have superior survival outcomes compared to pediatric brainstem gliomas. We conducted a retrospective data and tissue analysis of all adult patients (≥ 18 years old) with World Health Organization (WHO) Grade II
D A Mallory et al.
Journal of animal science, 88(11), 3568-3578 (2010-07-27)
Two experiments evaluated long-term progestin-based estrus-synchronization programs on the basis of potential for use in facilitating fixed-time AI in estrous cycling and prepubertal beef heifers. In Exp. 1, heifers were assigned to 1 of 2 treatments by age, BW, and
S A Tauck et al.
Theriogenology, 68(2), 162-167 (2007-06-05)
The objectives of this experiment were to compare estrous synchronization responses and AI pregnancy rates of beef heifers using protocols that included either CIDR or MGA as the progestin source. The hypotheses tested were that: (1) estrous synchronization responses after
Sarah Kelly Mortensen et al.
Analytica chimica acta, 586(1-2), 217-222 (2007-03-28)
A confirmatory method has been developed and validated for the determination of chlormadinone acetate (CMA), megestrol acetate (MGA), melengestrol acetate (MLA) and medroxyprogesterone acetate (MPA) in bovine and porcine plasma. Analytes are extracted from plasma samples using matrix-assisted liquid-liquid extraction
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