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Merck
CN

74148

Sigma-Aldrich

D-myo-Inositol 1,4,5-triphosphate tripotassium salt

≥80% (HPLC)

别名:

Ins(1,4,5)P3

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关于此项目

经验公式(希尔记法):
C6H12K3O15P3
化学文摘社编号:
分子量:
534.37
MDL编号:
UNSPSC代码:
12352108
PubChem化学物质编号:
NACRES:
NA.32
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方案

≥80% (HPLC)

表单

solid

储存温度

−20°C

SMILES字符串

O[C@@H]1[C@@H](OP(O)([O-])=O)[C@H](OP(O)([O-])=O)[C@@H](O)[C@@H](O)[C@H]1OP(O)([O-])=O.[K+].[K+].[K+]

InChI

1S/C6H15O15P3.3K/c7-1-2(8)5(20-23(13,14)15)6(21-24(16,17)18)3(9)4(1)19-22(10,11)12;;;/h1-9H,(H2,10,11,12)(H2,13,14,15)(H2,16,17,18);;;/q;3*+1/p-3/t1-,2+,3+,4-,5-,6-;;;/m1.../s1

InChI key

MQMSEISCCNPXIL-ZKVWPJASSA-K

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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分析证书(COA)

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M Hirata et al.
The Journal of biological chemistry, 264(34), 20303-20308 (1989-12-05)
A series of inositol 1,4,5-trisphosphate (IP3) analogs and positional isomers was examined to explore the structure-activity relationships among IP3 5-phosphatase, IP3 3-kinase, and the release of Ca2+. All analogs with additional groups on the 2nd position of IP3 inhibited the
I-Shan Chen et al.
Journal of biomedical science, 18, 2-2 (2011-01-08)
This study investigates whether protein kinase G (PKG), protein kinase A (PKA) and protein kinase C (PKC) are involved in the regulatory mechanisms of store-operated channel (SOC) in pulmonary arteries. Pulmonary artery smooth muscle cells (PASMCs) were enzymatically dissociated from
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The Biochemical journal, 428(3), 483-489 (2010-04-10)
IP3Rs (inositol 1,4,5-trisphosphate receptors) are the intracellular channels that mediate release of Ca2+ from the endoplasmic reticulum in response to the many stimuli that evoke Ins(1,4,5)P3 formation. We characterized and purified type 1 IP3R heterologously expressed in Sf9 insect cells
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eLife, 6 (2017-07-20)
FGF2 is secreted from cells by an unconventional secretory pathway. This process is mediated by direct translocation across the plasma membrane. Here, we define the minimal molecular machinery required for FGF2 membrane translocation in a fully reconstituted inside-out vesicle system.

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