生物来源
Streptomyces noursei
质量水平
方案
≥85% (HPLC)
表单
solid
颜色
white to light brown
溶解性
H2O: soluble 200 mg/mL
适用性
suitable for (selection agent for molecular genetic research work)
抗生素抗菌谱
Gram-negative bacteria
Gram-positive bacteria
fungi
mycobacteria
mycoplasma
parasites
viruses
yeast
作用机制
protein synthesis | interferes
储存温度
2-8°C
SMILES字符串
[S](=O)(=O)(O)O.N4[C@H]5[C@H](N=C4N[C@@H]6O[C@@H]([C@@H]([C@H]([C@H]6NC(=O)C[C@@H](N)CCCNC(=O)C[C@@H](N)CCCNC(=O)C[C@@H](N)CCCN)O)OC(=O)N)CO)C(=O)NC[C@H]5O.N1[C@H]2[C@H](N=C1N[C@@H]3O[C@@H]([C@@H]([C@H]([C@H]3NC(=O)C[C@@H](N)CCCN)O)OC(=O)N)CO)C(=O)NC[C@H]
InChI key
HEPYPTBGGNPPAP-SPCBHCMPSA-N
一般描述
Chemical structure: peptidyl nucleoside
应用
Noursethricin is used as a dominant selection antibiotic for genetically modified bacteria, yeasts, fungi, protozoa and plants.
生化/生理作用
Antifungal effective against Candida albicans. Candida species transformed with the gene encoding nourseothricin acetyltransferase (CaNAT1) were resistant to nourseothricin.
Nourseothricin inhibits biosynthesis and induces miscoding. Resistance to nourseothricin is mediated by the sat1 encoded N-acetyltransferase. Nourseothricin is inactivated by acetylation of the β-amino group of the β-lysin.
包装
10mg, 100mg
其他说明
Keep container tightly closed in a dry and well-ventilated place. Store under inert gas.
警示用语：
Warning
危险声明
危险分类
Acute Tox. 4 Oral
储存分类代码
13 - Non Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
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