75164
4-甲基伞形酮油酸酯
lipase substrate, ≥95% (HPCE), solid, suitable for fluorescence
别名:
油酸 4-甲基伞形酮酯
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关于此项目
经验公式（希尔记法）:
C28H40O4
化学文摘社编号:
分子量:
440.61
NACRES:
NA.21
PubChem Substance ID:
UNSPSC Code:
12352204
EC Number:
242-210-7
MDL number:
Beilstein/REAXYS Number:
4887028
产品名称
4-甲基伞形酮油酸酯, suitable for fluorescence, ≥95% (HPCE)
InChI key
NKQFKJYKCVDLPT-KHPPLWFESA-N
InChI
1S/C28H40O4/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-27(29)31-24-19-20-25-23(2)21-28(30)32-26(25)22-24/h10-11,19-22H,3-9,12-18H2,1-2H3/b11-10-
SMILES string
CCCCCCCC\C=C/CCCCCCCC(=O)Oc1ccc2C(C)=CC(=O)Oc2c1
assay
≥95% (HPCE)
form
solid
storage condition
protect from light
under inert gas
mp
37-38 °C (lit.)
solubility
2-methoxyethanol: soluble
DMSO: soluble
chloroform: soluble
fluorescence
λex 312 nm in methanol
λex 327 nm; λem 449 nm in 0.1 M phosphate pH 7.0 (lipase)
suitability
suitable for fluorescence
shipped in
wet ice
storage temp.
−20°C
Quality Level
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Application
4-甲基伞形油基油酸酯已被用于：
- 作为测定非特异性酯酶活性的底物
- 确定脂肪酶活性
- 作为评估胰腺脂肪酶抑制活性的底物
Other Notes
脂肪酶的荧光底物
Packaging
无底玻璃瓶。内含物在插入的融合锥体内。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
T J Van Berkel et al.
Biochimica et biophysica acta, 617(3), 446-457 (1980-03-21)
(1) Parenchymal and non-parenchymal cells were isolated from rat liver. The characteristics of acid lipase activity with 4-methylumbelliferyl oleate as substrate and acid cholesteryl esterase activity with cholesteryl[1-14C]oleate as substrate were investigated. The substrates were incorporated in egg yolk lecithin
Non-flavonoid phenolics from Averrhoa carambola fresh fruit
Jia X, et al.
Journal of functional foods, 32(1), 419-425 (2017)
Oleate lipase activity in Gardnerella vaginalis and reconsideration of existing biotype schemes
Moncla BJ and Pryke KM
BMC Microbiology, 9(1), 78-78 (2009)
Study of the hydrolysis of 4-methylumbelliferyl oleate by acid lipase and cholesteryl oleate by acid cholesteryl esterase in human leucocytes, fibroblasts and liver.
J F Koster et al.
Biochimica et biophysica acta, 618(1), 98-105 (1980-04-18)
Thavaree Thilavech et al.
BMC complementary and alternative medicine, 19(1), 242-242 (2019-09-07)
Cyanidin-3-rutinoside (C3R), a naturally occurring anthocyanin, possesses anti-oxidant, anti-hyperglycemic, anti-glycation and cardioprotective properties. However, its mechanisms responsible for anti-hyperlipidemic activity have not been fully identified. The aim of the study was to investigate the lipid-lowering mechanisms of C3R through inhibition
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