75633
四氧化锇 溶液
suitable for electron microscopy, 2% in H2O
别名:
氧化锇(IV)
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关于此项目
线性分子式:
OsO4
化学文摘社编号:
分子量:
254.23
NACRES:
NA.47
PubChem Substance ID:
UNSPSC Code:
12171500
MDL number:
Form:
solution
产品名称
四氧化锇 溶液, suitable for electron microscopy, 2% in H2O
InChI
1S/4O.Os
SMILES string
O=[Os](=O)(=O)=O
InChI key
VUVGYHUDAICLFK-UHFFFAOYSA-N
form
solution
reaction suitability
reagent type: oxidant
concentration
2% in H2O
technique(s)
electron microscopy: suitable
color
colorless to yellow
density
1.0 g/mL at 20 °C
1.0 g/mL at 20 °C
application(s)
hematology
histology
storage temp.
2-8°C
Quality Level
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Application
四氧化锇溶液被用作电子显微镜中的固定剂。
Biochem/physiol Actions
四氧化锇也被称为锇，主要用作组织的二次固定剂。该分子与脂类部分反应，并负责氧化脂肪酸的不饱和键。这种反应增加了生物样品的密度和对比度。在正常组织中，锇的存在导致强烈的黑色染色，正常眼睛可以看到。此外，它还可用作电子显微镜检查中的媒染剂（在后期与染色剂或染料结合的分子），从而增强铅染色。
General description
四氧化锇（OsO4）也被称为锇，是一种重的四面体对称分子。它可同时作为电镜的染料和非凝固型固定剂，主要用于组织病理学实验室中的生物组织检测。标本用四氧化锇再固定，以确保脂质保存。
signalword
Danger
Hazard Classifications
Acute Tox. 2 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Skin Irrit. 2
存储类别
6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
法规信息
监管及禁止进口产品
此项目有
Regulation of nitric-oxide production in hemocytes of the ascidian Phallusia nigra.
de Barros CM, et al.
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3-acetylpyridine-induced degeneration in the adult ascidian neural complex: Reactive and regenerative changes in glia and blood cells.
Medina BN, et al.
Developmental neurobiology, 75, 877-877 (2015)
Electron Microscopy: Principles and Techniques for Biologists (1999)
Bianca N S P Medina et al.
Developmental neurobiology, 75(8), 877-893 (2014-12-09)
Ascidians are interesting neurobiological models because of their evolutionary position as a sister-group of vertebrates and the high regenerative capacity of their central nervous system (CNS). We investigated the degeneration and regeneration of the cerebral ganglion complex of the ascidian
Carsten Købler et al.
Analytical and bioanalytical chemistry, 406(16), 3863-3873 (2014-01-23)
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