77636
酚酞β-D-葡萄糖苷酸
≥98% (TLC)
别名:
酚酞β-D-葡萄糖醛酸, 酚酞单-β-D-葡糖醛酸, 酚酞葡糖醛酸
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关于此项目
经验公式（希尔记法）:
C26H22O10
化学文摘社编号:
分子量:
494.45
Beilstein:
68526
MDL编号:
UNSPSC代码:
12352204
PubChem化学物质编号:
NACRES:
NA.83
生物来源
rabbit urine
方案
≥98% (TLC)
表单
powder
杂质
≤0.5% free phenolphthalein
≤6% water
溶解性
H2O: 0.1 g/mL, clear, light yellow
储存温度
−20°C
SMILES字符串
O[C@@H]1[C@@H](O)[C@@H](O[C@@H]([C@H]1O)C(O)=O)Oc2ccc(cc2)C3(OC(=O)c4ccccc34)c5ccc(O)cc5
InChI
1S/C26H22O10/c27-15-9-5-13(6-10-15)26(18-4-2-1-3-17(18)24(33)36-26)14-7-11-16(12-8-14)34-25-21(30)19(28)20(29)22(35-25)23(31)32/h1-12,19-22,25,27-30H,(H,31,32)/t19-,20-,21+,22-,25+,26?/m0/s1
InChI key
FXJYOZKDDSONLX-XADSOVDISA-N
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应用
β-glucuronidase test: suitable as substrate, for liver and bacterial enzymes
其他说明
Characterization of β-glucuronidase from Ampullaria
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
T. Tsukada et al.
Comparative Biochemistry and Physiology, 86B, 565-565 (1987)
B S Anand et al.
Alimentary pharmacology & therapeutics, 8(5), 559-562 (1994-10-01)
Phenolphthalein is widely used as a safe and effective laxative. After oral administration, phenolphthalein is absorbed in the small bowel and is conjugated in the liver to phenolphthalein glucuronide which passes into the colon where it is deconjugated and the
Tatsuyuki Marumo et al.
Journal of gastroenterology, 39(10), 981-987 (2004-11-19)
Hepatocytes in zone 1 of the hepatic lobule play a role in the uptake and biliary excretion of bile acids and organic anions under physiological conditions, and hepatocytes in zone 3 may play a role only when there is a
C V Rao et al.
Biochemical pharmacology, 42(12), 2323-2332 (1991-11-27)
A number of toxic chemicals affect the biliary excretory function of liver. Organochlorines and halomethanes are known to enhance bile flow. Despite the demonstration that a diversity of agents modify biliary function, the mechanism by which these chemicals manifest this
Z Gregus et al.
The Journal of pharmacology and experimental therapeutics, 225(2), 256-262 (1983-05-01)
Hepatic levels of uridine diphosphoglucuronic acid (UDPGA) in rats decreased substantially (greater than 80%) 40 min after galactosamine (GAL) (600 mg/kg i.p.) or after 1 hr of diethyl ether (DE) narcosis. Biliary excretion of several cholephils requiring glucuronidation before excretion
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