77636
酚酞β-D-葡萄糖苷酸
≥98% (TLC)
别名:
酚酞β-D-葡萄糖醛酸, 酚酞单-β-D-葡糖醛酸, 酚酞葡糖醛酸
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关于此项目
经验公式（希尔记法）:
C26H22O10
化学文摘社编号:
分子量:
494.45
UNSPSC Code:
12352204
NACRES:
NA.83
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
68526
InChI
1S/C26H22O10/c27-15-9-5-13(6-10-15)26(18-4-2-1-3-17(18)24(33)36-26)14-7-11-16(12-8-14)34-25-21(30)19(28)20(29)22(35-25)23(31)32/h1-12,19-22,25,27-30H,(H,31,32)/t19-,20-,21+,22-,25+,26?/m0/s1
SMILES string
O[C@@H]1[C@@H](O)[C@@H](O[C@@H]([C@H]1O)C(O)=O)Oc2ccc(cc2)C3(OC(=O)c4ccccc34)c5ccc(O)cc5
InChI key
FXJYOZKDDSONLX-XADSOVDISA-N
biological source
rabbit urine
assay
≥98% (TLC)
form
powder
impurities
≤0.5% free phenolphthalein, ≤6% water
solubility
H2O: 0.1 g/mL, clear, light yellow
storage temp.
−20°C
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Application
β-glucuronidase test: suitable as substrate, for liver and bacterial enzymes
Other Notes
Characterization of β-glucuronidase from Ampullaria
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
T. Tsukada et al.
Comparative Biochemistry and Physiology, 86B, 565-565 (1987)
W E Kurtin et al.
Analytical biochemistry, 147(2), 511-516 (1985-06-01)
A method for improving the assay of beta-glucuronidase in hepatic and gallbladder bile is described. The method uses ion-pair extraction with N,N,N-triheptyl-1-heptanaminium bromide to remove pigments and bile acids. Conjugated bilirubin, unconjugated bilirubin, and taurine and glycine conjugates of deoxycholic
Miklós Csala et al.
Biochemical pharmacology, 68(7), 1353-1362 (2004-09-04)
The transport of glucuronides across the endoplasmic reticulum membrane is an important step in the overall process of biotransformation, although the mechanism remains unclear and the participating transporters are unidentified. Using a rapid filtration assay in combination with liquid chromatography-mass
M Tugnait et al.
Journal of pharmaceutical and biomedical analysis, 9(10-12), 895-899 (1991-01-01)
Preliminary studies have been undertaken to evaluate the potential of immobilized phenylboronic acid (PBA) for the solid-phase extraction (SPE) of glucuronide metabolites from urine. These studies have demonstrated that immobilized PBA can be used to specifically extract phenolphthalein glucuronide (5
Z K Sharaiha et al.
Digestive diseases and sciences, 28(9), 827-832 (1983-09-01)
Phenolphthalein is an odorless, tasteless compound, poorly soluble in water, but readily soluble in alcohol or ether. Although its laxative activity was discovered in 1902, the mechanism of action remains unclear. Phenolphthalein has been found to be an ineffective laxative
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