77636
酚酞β-D-葡萄糖苷酸
≥98% (TLC)
别名:
酚酞β-D-葡萄糖醛酸, 酚酞单-β-D-葡糖醛酸, 酚酞葡糖醛酸
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关于此项目
经验公式（希尔记法）:
C26H22O10
化学文摘社编号:
分子量:
494.45
UNSPSC Code:
12352204
NACRES:
NA.83
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
68526
InChI
1S/C26H22O10/c27-15-9-5-13(6-10-15)26(18-4-2-1-3-17(18)24(33)36-26)14-7-11-16(12-8-14)34-25-21(30)19(28)20(29)22(35-25)23(31)32/h1-12,19-22,25,27-30H,(H,31,32)/t19-,20-,21+,22-,25+,26?/m0/s1
SMILES string
O[C@@H]1[C@@H](O)[C@@H](O[C@@H]([C@H]1O)C(O)=O)Oc2ccc(cc2)C3(OC(=O)c4ccccc34)c5ccc(O)cc5
InChI key
FXJYOZKDDSONLX-XADSOVDISA-N
biological source
rabbit urine
assay
≥98% (TLC)
form
powder
impurities
≤0.5% free phenolphthalein, ≤6% water
solubility
H2O: 0.1 g/mL, clear, light yellow
storage temp.
−20°C
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Application
β-glucuronidase test: suitable as substrate, for liver and bacterial enzymes
Other Notes
Characterization of β-glucuronidase from Ampullaria
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
T. Tsukada et al.
Comparative Biochemistry and Physiology, 86B, 565-565 (1987)
Adam G Staines et al.
Analytical biochemistry, 342(1), 45-52 (2005-06-17)
A primary reason for poor characterization of microsomal transport to date is the limitations of the measurement techniques used. Radiodetection provides sufficient sensitivity, but it can be applied only when labeled analogue is available. In this article, we report the
Takahiro Sasamoto et al.
Journal of gastroenterology and hepatology, 21(1 Pt 1), 26-31 (2006-05-19)
There are several reports on the biliary excretion of bile acids and organic anions in zone 1- and zone 3-injured rat liver, but the results are controversial. In order to dissolve the discrepancy between previous works about the role of
M Csala et al.
Biochemical pharmacology, 59(7), 801-805 (2000-03-16)
The physiological function of microsomal beta-glucuronidase is unclear. Substrates may be either glucuronides produced in the lumen of endoplasmic reticulum (ER) or those taken up by hepatocytes. In the latter case, efficient inward transport of glucuronides at the plasma membrane
J A Wilhelm et al.
Journal of chromatography, 578(2), 231-238 (1992-07-24)
A procedure is described to simultaneously quantitate phenolphthalein and its glucuronide metabolite from dog serum, urine and bile using high-performance liquid chromatography. The major advantages of this over pre-existing methods include direct analysis of the parent compound and glucuronide metabolite
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