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Merck
CN

77857

酮还原酶

recombinant, expressed in E. coli, ≥0.2 U/mg

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关于此项目

化学文摘社编号:
UNSPSC Code:
12352204
EC Number:
232-823-8
MDL number:
Specific activity:
≥0.2 U/mg
Recombinant:
expressed in E. coli
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recombinant

expressed in E. coli

form

powder

specific activity

≥0.2 U/mg

storage temp.

2-8°C

Application

酮还原酶可用于研究酮还原酶结构域的立体特异性 。它们可用于对α-氯醇的前体进行还原,该前体是多种药物化合物的合成中间体 。

Biochem/physiol Actions

酮还原酶(产品77857)以NADPH作为共底物还原4-氯乙酰乙酸酯。

Packaging

无底玻璃瓶。内含物在插入的融合锥体内。

Other Notes

1U 相当于在 pH 6.0,25°C 下每分钟还原 1 μmol 4-氯乙酰乙酸所需的酶量(共底物NADPH)。


pictograms

Health hazard

signalword

Danger

hcodes

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

常规特殊物品

此项目有



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Roselyne Castonguay et al.
Journal of the American Chemical Society, 130(35), 11598-11599 (2008-08-13)
Tylactone synthase (TYLS) is a modular polyketide synthase that catalyzes the formation of tylactone (1), the parent aglycone precursor of the macrolide antibiotic tylosin. TYLS modules 1 and 2 are responsible for the generation of antidiketide and triketide intermediates, respectively
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Applied microbiology and biotechnology, 78(6), 939-945 (2008-03-12)
Saccharomyces cerevisiae alcohol dehydrogenases responsible for NADH-, and NADPH-specific reduction of the furaldehydes 5-hydroxymethyl-furfural (HMF) and furfural have previously been identified. In the present study, strains overexpressing the corresponding genes (mut-ADH1 and ADH6), together with a control strain, were compared



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