82497
K-252a
from Nocardiopsis sp., ≥96.0% (HPLC)
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关于此项目
经验公式（希尔记法）:
C27H21N3O5
化学文摘社编号:
分子量:
467.47
MDL编号:
UNSPSC代码:
12352202
PubChem化学物质编号:
NACRES:
NA.77
生物来源
Nocardiopsis sp.
方案
≥96.0% (HPLC)
表单
powder
储存温度
2-8°C
SMILES字符串
[H][C@]12C[C@](O)(C(=O)OC)[C@](C)(O1)n3c4ccccc4c5c6CNC(=O)c6c7c8ccccc8n2c7c35
InChI
1S/C27H21N3O5/c1-26-27(33,25(32)34-2)11-18(35-26)29-16-9-5-3-7-13(16)20-21-15(12-28-24(21)31)19-14-8-4-6-10-17(14)30(26)23(19)22(20)29/h3-10,18,33H,11-12H2,1-2H3,(H,28,31)/t18-,26+,27+/m1/s1
InChI key
KOZFSFOOLUUIGY-SOLYNIJKSA-N
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包装
Bottomless glass bottle. Contents are inside inserted fused cone.
其他说明
A potent inhibitor of protein kinase C
警示用语：
Danger
危险声明
危险分类
Repr. 1B - STOT SE 2
靶器官
Eyes,Central nervous system
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
法规信息
新产品
此项目有
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The Journal of antibiotics, 39(8), 1059-1065 (1986-08-01)
K-252a, a metabolite isolated from the culture broth of Nocardiopsis sp. K-252a, was found to exhibit an extremely potent inhibitory activity on protein kinase C. The IC50 value was 32.9 nM.
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