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Merck
CN

85561

精脒

≥99.0% (GC)

别名:

1,8-二氨基-4-氮杂辛烷, N-(3-氨基丙基)-1,4-丁烷

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关于此项目

线性分子式:
NH2(CH2)3NH(CH2)4NH2
化学文摘社编号:
分子量:
145.25
EC Number:
204-689-0
UNSPSC Code:
12352200
PubChem Substance ID:
Beilstein/REAXYS Number:
1698591
MDL number:
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InChI key

ATHGHQPFGPMSJY-UHFFFAOYSA-N

InChI

1S/C7H19N3/c8-4-1-2-6-10-7-3-5-9/h10H,1-9H2

SMILES string

NCCCCNCCCN

assay

≥99.0% (GC)

impurities

≤0.2% spermine

refractive index

n20/D 1.479 (lit.)

mp

22-25 °C

density

0.925 g/mL at 25 °C (lit.)

Gene Information

rat ... Ppm1a(24666)

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Biochem/physiol Actions

抑制神经元型一氧化氮合成酶(nNOS)。结合和沉淀DNA,可用于DNA结合蛋白纯化。激活T4聚核苷酸激酶活性。
抑制神经元型一氧化氮合成酶(nNOS)。结合和沉淀DNA;激活T4聚核苷酸激酶活性。

Other Notes

Polyamines: Review

Disclaimer

如果需要无菌溶液,则应采用无菌过滤而非高压灭菌。时间一长,亚精胺将发生脱氨基作用;溶液应采用冷冻保存。通常需要配制新溶液。

pictograms

Corrosion

signalword

Danger

hcodes

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1B

存储类别

8A - Combustible corrosive hazardous materials

wgk

WGK 3

flash_point_f

233.6 °F - closed cup

flash_point_c

112 °C - closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

法规信息

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分析证书(COA)

Lot/Batch Number

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Polyamines.
C W Tabor et al.
Annual review of biochemistry, 53, 749-790 (1984-01-01)
Anita Nielsen et al.
Marine drugs, 10(11), 2584-2595 (2012-12-04)
Staphylococcus aureus is a serious human pathogen that employs a number of virulence factors as part of its pathogenesis. The purpose of the present study was to explore marine bacteria as a source of compounds that modulate virulence gene expression
Varun K Gupta et al.
Nature neuroscience, 16(10), 1453-1460 (2013-09-03)
Age-dependent memory impairment is known to occur in several organisms, including Drosophila, mouse and human. However, the fundamental cellular mechanisms that underlie these impairments are still poorly understood, effectively hampering the development of pharmacological strategies to treat the condition. Polyamines
Eugenia Morselli et al.
Aging, 1(12), 961-970 (2010-02-17)
Although autophagy has widely been conceived as a self-destructive mechanism that causes cell death, accumulating evidence suggests that autophagy usually mediates cytoprotection, thereby avoiding the apoptotic or necrotic demise of stressed cells. Recent evidence produced by our groups demonstrates that
Maria Kostakioti et al.
Cold Spring Harbor perspectives in medicine, 3(4), a010306-a010306 (2013-04-03)
Biofilm formation constitutes an alternative lifestyle in which microorganisms adopt a multicellular behavior that facilitates and/or prolongs survival in diverse environmental niches. Biofilms form on biotic and abiotic surfaces both in the environment and in the healthcare setting. In hospital

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