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Merck
CN

86510

睾酮乙酸酯

purum, ≥99.0% (HPLC)

别名:

17β-乙酰氧基-4-雄甾烯-3-酮, 17β-羟基-4-雄甾烯-3-酮-17-乙酸酯, 4-雄甾烯-17β-醇-3-酮-17-乙酸酯, 醋酸睾酮

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关于此项目

经验公式(希尔记法):
C21H30O3
化学文摘社编号:
分子量:
330.46
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
213-876-6
MDL number:
Beilstein/REAXYS Number:
2062555
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grade

purum

assay

≥99.0% (HPLC)

optical activity

[α]20/D +88±2°, c = 1% in ethanol

drug control

USDEA Schedule IIIN; regulated under CDSA - not available from Sigma-Aldrich Canada

mp

139-141 °C

SMILES string

[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]4(C)[C@H](CC[C@@]24[H])OC(C)=O

Application

Testosterone acetate was used to prepare thiosemicarbazone ligand and as a standard to analyze the androgenic steroids from cattle hair by LC/MS/MS.

Biochem/physiol Actions

Testosterone is a steroid sex hormone that has physiological roles in both sexes. It modulates the development of brain structure and differentiation of neurons during intrauterine development. It activates signaling by androgen receptors that results in the formation of male sex organs, growth of facial hair and muscles.

Other Notes

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H Miyamoto et al.
Current cancer drug targets, 12(1), 14-22 (2011-11-25)
Unlike prostate and breast cancers, urothelial carcinoma of the urinary bladder is not yet considered as an endocrine-related neoplasm, and hormonal therapy for bladder cancer remains experimental. Nonetheless, there is increasing evidence indicating that nuclear hormone receptor signals are implicated
A Murugkar et al.
Metal-based drugs, 6(3), 177-182 (2008-05-14)
Testosterone acetate thiosemicarbazone (TATSC, 17-beta-hydroxyandrost-4-one acetate thiosemicarbazone) was synthesized and characterized by single crystal X-ray structure determination. The copper and platinum complexes of this steroid derivative were synthesized and characterized by spectroscopy and electrochemiatry. The in vitro activity of these
Jaroslava Durdiakova et al.
Acta neurobiologiae experimentalis, 71(4), 434-454 (2012-01-13)
Testosterone is a steroid sex hormone with an important role in the physiology in both sexes. It is involved in the development of morphological and functional parameters of the body via multiple molecular mechanisms. Intensive research focused on testosterone reveals