form
suspension
storage temp.
2-8°C
正在寻找类似产品? 访问 产品对比指南
General description
5 x 0.1 ml settled resin of endoglycosidase IgGZERO (EndoS) immobilized on highly crosslinked agarose. Agarose resin is suspended in 20% ethanol/water (V/V)
Application
DeGlycIT MicroSpin columns (deglycosylates up to 0.5 mg IgG, 5 columns) can be used for antibody characterization.
Biochem/physiol Actions
DeGlycIT MicroSpin columns comprise of pre-filled endoglycosidase IgGZERO (EndoS) enzyme covalently coupled to highly cross-linked agarose. IgGZERO is a bacterial enzyme isolated from Streptococcus pyogenes, which possess hydrolytic activity specific for IgG bound glycans and cleaves bound IgG from IgG Fc receptors without damaging the native cells.
Analysis Note
Enzymatic activity: corresponds to requirements
Other Notes
1 ml of settled enzyme immobilized agarose resin removes 95% of 5 mg of human IgG Fc glycans in 15 minutes at 25°C, pH 7.2 as monitored by SDS-PAGE.
signalword
Danger
hcodes
Hazard Classifications
Flam. Liq. 2
存储类别
3 - Flammable liquids
wgk
WGK 3
flash_point_f
57.2 °F - closed cup
flash_point_c
14.0 °C - closed cup
法规信息
新产品
此项目有
Michele S Y Tan et al.
PloS one, 15(1), e0227341-e0227341 (2020-01-11)
Clan CA cysteine proteases, also known as papain-like proteases, play important roles throughout the malaria parasite life cycle and are therefore potential drug targets to treat this disease and prevent its transmission. In order to study the biological function of
Jonathan J Goodfellow et al.
Journal of the American Chemical Society, 134(19), 8030-8033 (2012-05-04)
Protein endoglycosidases are useful for biocatalytic alteration of glycans on protein surfaces, but the currently limited selectivity of endoglycosidases has prevented effective manipulation of certain N-linked glycans widely found in nature. Here we reveal that a bacterial endoglycosidase from Streptococcus
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持