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Merck
CN

91252

2-Deoxyribose 5-phosphate Aldolase, E. coli K12, recombinant K12 from E. coli

≥2 U/mg

别名:

DERA, Deoxyriboaldolase

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关于此项目

化学文摘社编号:
UNSPSC Code:
12352204
NACRES:
NA.54
EC 号:
4.1.2.4.
MDL number:
Specific activity:
≥2 U/mg
Recombinant:
expressed in E. coli
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recombinant

expressed in E. coli

form

crystals, powder

specific activity

≥2 U/mg

shipped in

wet ice

storage temp.

−20°C

Quality Level

Biochem/physiol Actions

Deoxyriboaldolase catalyzes the condensation of acetaldehyde and glyceraldehyde 3-phosphate to 2-deoxyribose 5-phosphate.

Other Notes

1 U corresponds to the amount of enzyme which converts 1 μmol 2-Deoxy-D-ribose-5-phosphate per minute at pH 7.5 and 25°C
The enzyme catalyzes the reversible cleavage of 2-deoxyribose-5-phosphate to acetaldehyde and D-glyceraldehyde-3-phosphate

存储类别

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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Francisco S Domingues et al.
Protein engineering, design & selection : PEDS, 17(6), 537-543 (2004-08-21)
Experimentally determined protein structures have been classified in different public databases according to their structural and evolutionary relationships. Frequently, alternative structural models, determined using X-ray crystallography or NMR spectroscopy, are available for a protein. These models can present significant structural
Robert A Alberty
Biochemistry, 43(30), 9840-9845 (2004-07-28)
Recent thermodynamic measurements have made it possible to calculate the apparent equilibrium constants of the ribonucleoside diphosphate reductase reaction and the ribonucleoside triphosphate reductase reaction with various reducing agents. Third law heat capacity measurements on crystals of d-ribose and other
Stefan Jennewein et al.
Biotechnology journal, 1(5), 537-548 (2006-08-08)
Aldolases are emerging as powerful and cost efficient tools for the industrial synthesis of chiral molecules. They catalyze enantioselective carbon-carbon bond formations, generating up to two chiral centers under mild reaction conditions. Despite their versatility, narrow substrate ranges and enzyme
Naeem Rashid et al.
Journal of bacteriology, 186(13), 4185-4191 (2004-06-19)
Numerous bacteria and mammalian cells harbor two enzymes, phosphopentomutase (PPM) and 2-deoxyribose 5-phosphate aldolase (DERA), involved in the interconversion between nucleosides and central carbon metabolism. In this study, we have examined the presence of this metabolic link in the hyperthermophilic
Michio Hirano et al.
The neurologist, 10(1), 8-17 (2004-01-15)
Mitochondrial encephalomyopathies are clinically and genetically heterogeneous because mitochondria are the products of 2 genomes: mitochondrial DNA (mtDNA) and nuclear DNA (nDNA). Among the mendelian-inherited mitochondrial diseases are defects of intergenomic communication, disorders due to nDNA mutations that cause depletion

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