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Merck
CN

93426

Triton™ X-100

BioXtra

别名:

4-(1,1,3,3-四甲基丁基)苯基-聚乙二醇, t-辛基苯氧基聚乙氧基乙醇, 聚乙二醇 叔辛基苯醚

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线性分子式:
t-Oct-C6H4-(OCH2CH2)xOH, x= 9-10
化学文摘社编号:
9036-19-5
PubChem Substance ID:
329770232
UNSPSC Code:
12352200
Beilstein/REAXYS Number:
2315025
MDL number:
MFCD00128254

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grade

Molecular Biology

description

non-ionic

product line

BioXtra

form

liquid

mol wt

micellar avg mol wt 80,000, average mol wt 625

aggregation number

100-155

technique(s)

flow cytometry: suitable, immunofluorescence: suitable, permeability assay: suitable

impurities

DNases, none detected, RNases, none detected, phosphatases, none detected, proteases, none detected

ign. residue

≤0.2%

CMC

0.2-0.9 mM (20-25°C)

transition temp

cloud point 65 °C, pour point ~7 °C

solubility

H2O: 0.005 M at 20 °C, clear, colorless

density

1.065 g/mL at 20 °C

anion traces

chloride (Cl-): ≤50 mg/kg, sulfate (SO42-): ≤50 mg/kg

cation traces

Ca: ≤10 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg, Cr: ≤5 mg/kg, Cu: ≤5 mg/kg, Fe: ≤5 mg/kg, K: ≤500 mg/kg, Mg: ≤5 mg/kg, Mn: ≤5 mg/kg, Na: ≤500 mg/kg, Ni: ≤5 mg/kg, Pb: ≤5 mg/kg, Zn: ≤5 mg/kg

HLB

13.5

storage temp.

2-8°C

SMILES string

CC(C)(C)CC(C)(C)c1ccc(OCCOCCOCCOCCOCCOCCOCCO)cc1

InChI

1S/C28H50O8/c1-27(2,3)24-28(4,5)25-6-8-26(9-7-25)36-23-22-35-21-20-34-19-18-33-17-16-32-15-14-31-13-12-30-11-10-29/h6-9,29H,10-24H2,1-5H3

InChI key

HNLXNOZHXNSSPN-UHFFFAOYSA-N

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General description

Triton™ X-100 is a non-ionic surfactant that aids the recovery of membrane-bound proteins under mild non-denaturing conditions.

Application

Suitable for extraction of membrane-bound proteins

Biochem/physiol Actions

广泛使用的非离子型表面活性剂，用于在温和的非变性条件下回收膜组分。
Triton™ X-100 compromises the integrity of the lipid bilayer by disrupting the polar head group on the hydrogen bonding. The detergent monomer inserts itself into the lipid bilayer resulting in over-permeabilization and disruption of the cell structure.

Legal Information

Triton is a trademark of The Dow Chemical Company or an affiliated company of Dow

signalword

Danger

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Irrit. 2

存储类别

10 - Combustible liquids

wgk

WGK 3

flash_point_f

483.8 °F - closed cup

flash_point_c

251 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCBH2984V
BCBD2755V
BCBB4485V
BCBC7803
BCBB4485

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Microinjection into Xenopus oocytes: equipment.
M J Hitchcock et al.
Methods in enzymology, 152, 276-284 (1987-01-01)
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Proceedings of the National Academy of Sciences of the United States of America, 107(39), 16783-16787 (2010-09-15)
Changes in HeLa cell morphology, membrane permeability, and viability caused by the presence of Triton X-100 (TX100), a nonionic surfactant, were studied by scanning electrochemical microscopy (SECM). No change in membrane permeability was found at concentrations of 0.15 mM or
Wentao Li et al.
Virus research, 235, 6-13 (2017-04-02)
Porcine epidemic diarrhea virus (PEDV) is an emerging pathogenic coronavirus that causes a significant economic burden to the swine industry. The virus infects the intestinal epithelium and causes villous atrophy, resulting in diarrhea and dehydration. Interaction of the viral spike
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In experimental autoimmune encephalomyelitis (EAE), an animal model for multiple sclerosis (MS), loss of the blood-brain barrier (BBB) tight junction (TJ) protein claudin-3 correlates with immune cell infiltration into the CNS and BBB leakiness. Here we show that sealing BBB
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Previous investigators reported that epiretinal membranes isolated from patients with proliferative vitreoretinopathy (PVR) express various platelet-derived growth factor (PDGF) family members and PDGF receptors (PDGFRs) (Cui, J.Z., Chiu, A., Maberley, D., Ma, P., Samad, A., Matsubara, J.A., 2007. Stage specificity
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