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Merck
CN

94333

Uridine 5′-diphosphogalactose disodium salt

≥98.0% (HPLC)

别名:

UDP-Gal, Uridine-diphosphate-galactose disodium salt, Uridine[5’]diphospho[1]-α-D-galactopyranose disodium salt

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关于此项目

经验公式(希尔记法):
C15H22N2Na2O17P2
化学文摘社编号:
分子量:
610.27
PubChem Substance ID:
UNSPSC Code:
41106305
Beilstein/REAXYS Number:
5374254
MDL number:
Assay:
≥98.0% (HPLC)
Form:
powder
Solubility:
H2O: 50 mg/mL, clear, colorless
Storage temp.:
−20°C
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assay

≥98.0% (HPLC)

form

powder

impurities

≤5% solvent (ethanol), ≤6% water

solubility

H2O: 50 mg/mL, clear, colorless

storage temp.

−20°C

SMILES string

[Na+].[Na+].OC[C@H]1O[C@@H](OP([O-])(=O)OP([O-])(=O)OC[C@H]2OC([C@H](O)[C@@H]2O)N3C=CC(=O)NC3=O)[C@H](O)[C@@H](O)[C@H]1O

InChI

1S/C15H24N2O17P2.2Na/c18-3-5-8(20)10(22)12(24)14(32-5)33-36(28,29)34-35(26,27)30-4-6-9(21)11(23)13(31-6)17-2-1-7(19)16-15(17)25;;/h1-2,5-6,8-14,18,20-24H,3-4H2,(H,26,27)(H,28,29)(H,16,19,25);;/q;2*+1/p-2/t5-,6-,8+,9-,10+,11-,12-,13?,14?;;/m1../s1

InChI key

PKJQEQVCYGYYMM-OUJOOSCPSA-L

Application

Uridine 5dATP-diphosphogalactose (UDP-Gal) is a sugar-nucleotide substrate of galactosyltransferase(s) involved in the addition of galatose (galactosylation) molecules to N-linked and O-linked oligosaccharides and glycerolipids. UDP-Gal and its analogues are used to study the distribution, specificity and kinetics of galactosyltransferase(s).


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存储类别

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Karine Descroix et al.
Organic & biomolecular chemistry, 9(6), 1855-1863 (2011-01-27)
Structural analogues and mimics of the natural sugar-nucleotide UDP-galactose (UDP-Gal) are sought after as chemical tools for glycobiology and drug discovery. We have recently developed a novel class of galactosyltransferase (GalT) inhibitors derived from UDP-Gal, bearing an additional substituent at
Subcellular localization of UDP-GlcNAc, UDP-Gal and SLC35B4 transporters.
Maszczak-Seneczko D, Olczak T, Olczak M.
Acta Biochimica Polonica, 58(3), 416-419 (2011)
Eric R Moellering et al.
Trends in plant science, 16(2), 98-107 (2010-12-15)
Galactoglycerolipids are the predominant lipid building blocks of chloroplast membranes and are essential for plant growth. Plant chloroplasts harbor a constitutive set of UDP-Gal-dependent lipid galactosyltransferases that are responsible for the bulk of galactoglycerolipid biosynthesis. A set of paralogs is



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货号GTIN
94333-10MG04061833267035