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Merck
CN

A0793

Anti-Dog IgG (whole molecule)–Alkaline Phosphatase antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

别名:

Rabbit Anti-Dog IgG (whole molecule)–AP

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
Conjugate:
alkaline phosphatase conjugate
Clone:
polyclonal
Application:
DB, ELISA (d), WB CL
Citations:
8
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biological source

rabbit

conjugate

alkaline phosphatase conjugate

antibody form

IgG fraction of antiserum

antibody product type

secondary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

dog

technique(s)

direct ELISA: 1:6,000, dot blot: 1:4,000, western blot (chemiluminescent): 1:4,000

shipped in

wet ice

storage temp.

2-8°C

target post-translational modification

unmodified

Quality Level

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General description

An immunoglobulin has two heavy chain and two light chain connected by disulfide bond. It mainly helps in immune defense. It is a glycoprotein. IgG is a major class of immunoglobulin. In dogs four subclasses of IgG (IgG1 -IgG4) are present.
Dog IgGs are glycoprotein antibodies that regulate several immunological responses. Canine IgGs can be used as markers for detecting immune-mediated haemolytic anaemia, adverse food reactions and also for assessing the risk of L. infantum transmission in dogs.

Immunogen

IgG isolated from pooled normal dog serum

Application

Anti-Dog IgG (whole molecule)−Alkaline Phosphatase antibody produced in rabbit has been used in enzyme-linked immunosorbent assay (ELISA), and immunoblotting.

Biochem/physiol Actions

Anti-Dog IgG (whole molecule) antibody is specific for IgG in dogs when tested against normal dog serum and dog IgG by double-diffusion and immunoelectrophoretic assays prior to conjugation.
Immunoglobulin G (IgG) participates in hypersensitivity type II and type III.

Physical form

Solution in 0.05 M Tris, pH 8.0, containing 1% bovine serum albumin, 1 mM MgCl2 and 15 mM sodium azide

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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存储类别

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

常规特殊物品
低风险生物材料
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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C Sriwichai et al.
The Journal of small animal practice, 52(9), 476-483 (2011-09-08)
Canine allo- or autoantibodies are clinically important, but attachment of these immunoglobulin G (IgG) antibodies does not produce observable haemagglutination. Antibody to canine globulins is required to demonstrate sensitisation of red blood cells. Commercial reagents are available, but these often
Delivery of recombinant gene product to canine brain with the use of microencapsulation
Barsoum SC, et al.
The Journal of Laboratory and Clinical Medicine, 142(6), 399-413 (2003)
Joseph A Impellizeri et al.
Journal of translational medicine, 16(1), 349-349 (2018-12-13)
we have recently shown that Tel-eVax, a genetic vaccine targeting dog telomerase (dTERT) and based on Adenovirus (Ad)/DNA Electro-Gene-Transfer (DNA-EGT) technology can induce strong immune response and increase overall survival (OS) of dogs affected by multicentric Diffuse Large B cell
A Bead-Based Flow Cytometric Assay for Monitoring Yersinia pestis Exposure in Wildlife
Chandler JC, et al.
Journal of Clinical Microbiology, 56(7) (2018)
Michaela Vlkova et al.
PLoS neglected tropical diseases, 5(10), e1344-e1344 (2011-10-25)
Phlebotomine sand flies are blood-sucking insects that can transmit Leishmania parasites. Hosts bitten by sand flies develop an immune response against sand fly salivary antigens. Specific anti-saliva IgG indicate the exposure to the vector and may also help to estimate

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