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Merck
CN

A2804

氨苄西林 钠盐

powder

别名:

氨苄青霉素 钠盐

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关于此项目

经验公式(希尔记法):
C16H18N3NaO4S
化学文摘社编号:
分子量:
371.39
EC Number:
200-708-1
UNSPSC Code:
12352200
PubChem Substance ID:
Beilstein/REAXYS Number:
4119211
MDL number:
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sterility

γ-irradiated

form

powder

color

white to slight yellow

mp

215 °C (dec.) (lit.)

solubility

sterile water: 5-20 mg/mL (as a stock solution)

antibiotic activity spectrum

Gram-negative bacteria, Gram-positive bacteria

storage temp.

2-8°C

SMILES string

[Na+].CC1(C)SC2[C@H](NC(=O)[C@H](N)c3ccccc3)C(=O)N2[C@H]1C([O-])=O

InChI

1S/C16H19N3O4S.Na/c1-16(2)11(15(22)23)19-13(21)10(14(19)24-16)18-12(20)9(17)8-6-4-3-5-7-8;/h3-7,9-11,14H,17H2,1-2H3,(H,18,20)(H,22,23);/q;+1/p-1/t9-,10-,11+,14-;/m1./s1

InChI key

KLOHDWPABZXLGI-YWUHCJSESA-M

General description

Chemical structure: β-lactam

Application

Recommended for use in molecular biology applications at 20-50 μg/ml.

Biochem/physiol Actions

作用方式:该β-内酰胺抗生素通过灭活位于细菌的细胞膜内表面的转肽酶从而抑制细菌细胞壁合成。

耐药性机制:β-内酰胺酶切开氨苄青霉素的β-内酰胺环,使其失去活性。

抗菌谱:包括革兰氏阳性菌(类似青霉素)和革兰氏阴性菌(类似四环素和氯霉素)。

Preparation Note

Prepare stock solutions directly in the vial at any concentration in the recommended range. Stock solutions should be stored at −20 °C. Stable at 37 °C for 3 days.

Analysis Note

USP potency testing is carried out on control vials after γ-irradiation to assure full biological activity (except where noted).


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pictograms

Health hazard

signalword

Danger

hcodes

Hazard Classifications

Resp. Sens. 1A - Skin Sens. 1A

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

法规信息

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