A2804
氨苄西林 钠盐
powder
别名:
氨苄青霉素 钠盐
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关于此项目
经验公式（希尔记法）:
C16H18N3NaO4S
化学文摘社编号:
分子量:
371.39
EC Number:
200-708-1
UNSPSC Code:
12352200
PubChem Substance ID:
Beilstein/REAXYS Number:
4119211
MDL number:
InChI key
KLOHDWPABZXLGI-YWUHCJSESA-M
InChI
1S/C16H19N3O4S.Na/c1-16(2)11(15(22)23)19-13(21)10(14(19)24-16)18-12(20)9(17)8-6-4-3-5-7-8;/h3-7,9-11,14H,17H2,1-2H3,(H,18,20)(H,22,23);/q;+1/p-1/t9-,10-,11+,14-;/m1./s1
SMILES string
[Na+].CC1(C)SC2[C@H](NC(=O)[C@H](N)c3ccccc3)C(=O)N2[C@H]1C([O-])=O
sterility
γ-irradiated
form
powder
color
white to slight yellow
mp
215 °C (dec.) (lit.)
solubility
sterile water: 5-20 mg/mL (as a stock solution)
antibiotic activity spectrum
Gram-negative bacteria, Gram-positive bacteria
storage temp.
2-8°C
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General description
Chemical structure: β-lactam
Application
Recommended for use in molecular biology applications at 20-50 μg/ml.
Biochem/physiol Actions
作用方式：该β-内酰胺抗生素通过灭活位于细菌的细胞膜内表面的转肽酶从而抑制细菌细胞壁合成。
耐药性机制：β-内酰胺酶切开氨苄青霉素的β-内酰胺环,使其失去活性。
抗菌谱：包括革兰氏阳性菌(类似青霉素)和革兰氏阴性菌(类似四环素和氯霉素)。
耐药性机制：β-内酰胺酶切开氨苄青霉素的β-内酰胺环,使其失去活性。
抗菌谱：包括革兰氏阳性菌(类似青霉素)和革兰氏阴性菌(类似四环素和氯霉素)。
Preparation Note
Prepare stock solutions directly in the vial at any concentration in the recommended range. Stock solutions should be stored at −20 °C. Stable at 37 °C for 3 days.
Analysis Note
USP potency testing is carried out on control vials after γ-irradiation to assure full biological activity (except where noted).
signalword
Danger
hcodes
Hazard Classifications
Resp. Sens. 1A - Skin Sens. 1A
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
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