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About This Item
经验公式（希尔记法）:
C16H17NO3 · HCl
CAS Number:
分子量:
307.77
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77
方案
≥98% (HPLC)
表单
powder
储存条件
desiccated
颜色
off-white to tan
溶解性
H2O: soluble ~9 mg/mL
创始人
Abbott
储存温度
−20°C
SMILES字符串
Cl.NC[C@@H]1O[C@@H](Cc2c(O)c(O)ccc12)c3ccccc3
InChI
1S/C16H17NO3.ClH/c17-9-15-11-6-7-13(18)16(19)12(11)8-14(20-15)10-4-2-1-3-5-10;/h1-7,14-15,18-19H,8-9,17H2;1H/t14-,15-;/m0./s1
InChI key
PQPGUUQPTSMLKU-YYLIZZNMSA-N
应用
A-68930 hydrochloride has been used as a D1 receptor agonist to study its effect on striatal phosphorylation of cyclin-dependent kinase 5 (Cdk5) at Tyr15 in mice. It has also been used to study its effect on the cAMP accumulation in C-terminal mutant D1Rs in transfected HEK 293 cells.
生化/生理作用
A-68930 hydrochloride is a cell-membrane impermeable selective D1 dopamine receptor agonist.
A-68930 hydrochloride might possess antipsychotic properties.
特点和优势
This compound was developed by Abbott. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
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