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B4894

苄基2-乙酰氨基-2-脱氧-α-D-半乳糖苷

Name: 苄基2-乙酰氨基-2-脱氧-α-<sc>D</sc>-半乳糖苷
Brand: SIGMA

O-glycosylation inhibitor, ≥97% (TLC)

别名:

苄基-α-乙酰半乳糖胺, α-D-GalNAc-1→OCH₂Ph, 乙酰半乳糖胺α-O-苄基, 乙酰半乳糖胺-O-bn, 苄基N-乙酰基-α-D-半乳糖胺

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关于此项目

经验公式（希尔记法）:

C₁₅H₂₁NO₆ · xH₂O

化学文摘社编号:

3554-93-6

分子量:

311.33 (anhydrous basis)

NACRES:

NA.25

PubChem Substance ID:

24891802

UNSPSC Code:

12352201

MDL number:

MFCD00057920

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属性

Quality Level

100

assay

≥97% (TLC)

form

powder

color

white to off-white

mp

204-208 °C

solubility

methanol: soluble 10 mg/mL, clear

storage temp.

−20°C

SMILES string

CC(N[C@H]([C@H]([C@H]1O)O)[C@H](O[C@@H]1CO)OCC2=CC=CC=C2)=O

InChI

InChI=1S/C15H21NO6/c1-9(18)16-12-14(20)13(19)11(7-17)22-15(12)21-8-10-5-3-2-4-6-10/h2-6,11-15,17,19-20H,7-8H2,1H3,(H,16,18)/t11-,12-,13+,14-,15+/m1/s1

InChI key

SKOZFDIGKDPQBO-QMIVOQANSA-N

说明

Biochem/physiol Actions

苄基-N-乙酰基-α- 氨基半乳糖苷抑制糖基转移酶将葡萄糖胺掺入O-聚糖中。抑制乳腺癌细胞系MDF-7中粘蛋白的生物合成并抑制MUC1的表达。

Other Notes

为了全面了解我们针对客户研究提供的各种二糖产品，建议您访问我们的碳水化合物分类页面。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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[Correlation of MUC1 expression to adhesion of breast cancer cell line MDA-MB-231].

Li Lu et al.

Ai zheng = Aizheng = Chinese journal of cancer, 23(11), 1294-1296 (2004-11-04)

Recent researches found that an abundant production of mucin protein well correlates with tumor cell metastasis. This study was to investigate inhibitory effect of benzyl-alpha-GalNAc on production of mucin 1 (MUC1), and on adhesion and invasion of breast cancer cell

Inhibition of CD44 N- and O-linked glycosylation decreases endometrial cell lines attachment to peritoneal mesothelial cells.

Allison K Rodgers et al.

Fertility and sterility, 95(2), 823-825 (2010-10-26)

The attachment of endometrial epithelial cells (EECs) and endometrial stromal cells (ESCs) to peritoneal mesothelial cells (PMCs) with and without inhibition of N- and O-linked glycosylation, the viability of EECs and ESCs, and the expression of CD44 surface density were

Antiadhesive character of mucin O-glycans at the apical surface of corneal epithelial cells.

Mika Sumiyoshi et al.

Investigative ophthalmology & visual science, 49(1), 197-203 (2008-01-04)

Prolonged contact of opposite mucosal surfaces, which occurs on the ocular surface, oral cavity, reproductive tract, and gut, requires a specialized apical cell surface that prevents adhesion. The purpose of this study was to evaluate the contribution of mucin O-glycans

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全球贸易项目编号

货号	GTIN
B4894-25MG	04061833433522
B4894-100MG	04061832960791
B4894-500MG	04061832960807