C7270
头孢孟多酯钠
~95%
别名:
Cefamandole formate sodium salt
登录 查看组织和合同定价。
选择尺寸
关于此项目
线性分子式:
C19H17N6O6S2Na
化学文摘社编号:
分子量:
512.49
UNSPSC Code:
51101500
PubChem Substance ID:
EC Number:
255-877-4
MDL number:
assay
~95%
mode of action
cell wall synthesis | interferes
SMILES string
[Na+].Cn1nnnc1SCC2=C(N3C(SC2)[C@H](NC(=O)[C@H](OC=O)c4ccccc4)C3=O)C([O-])=O
InChI
1S/C19H18N6O6S2.Na/c1-24-19(21-22-23-24)33-8-11-7-32-17-12(16(28)25(17)13(11)18(29)30)20-15(27)14(31-9-26)10-5-3-2-4-6-10;/h2-6,9,12,14,17H,7-8H2,1H3,(H,20,27)(H,29,30);/q;+1/p-1/t12-,14-,17-;/m1./s1
InChI key
ICZOIXFFVKYXOM-YCLOEFEOSA-M
正在寻找类似产品? 访问 产品对比指南
General description
Chemical structure: β-lactam
Application
Cefamandole is used to study the effects of expression and inhibition of PBP 2A and other penicillin-binding proteins (PDPs) on bacterial cell wall mucopeptide synthesis.
Biochem/physiol Actions
Cefamandole nafate inhibits bacterial cell wall synthesis by inhibiting PBP 2A and other penicillin-binding proteins. Cefamandole nafate has been shown to be rapidly converted to cefamandolein bacteriological media .
Physical form
sodium carbonate: approx. 5%
signalword
Danger
hcodes
Hazard Classifications
Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
法规信息
涉药品监管产品
此项目有
D H Livingston et al.
Surgery, gynecology & obstetrics, 168(2), 138-142 (1989-02-01)
Hemorrhagic shock has been associated with an increased risk of infection after injury. The immediate and long term effects of hemorrhagic shock without tissue injury on the susceptibility of an animal to infection and the efficacy of antibiotic prophylaxis to
P B Issopoulos et al.
Acta pharmaceutica Hungarica, 66(2), 89-94 (1996-03-01)
A sensitive, accurate, precise and the same time simple and rapid method for the colorimetric determination of some cephalosporins of the second and third generations, such as: cefoxitin sodium (CFXT), cefaclor (CFCL), cefamandole nafate (CFMD), ceforanide l-lysine (CFRN), cefotaxime sodium
R S Bennion et al.
The Journal of cardiovascular surgery, 26(3), 270-274 (1985-05-01)
A blinded, randomized, prospective study of 38 chronic renal failure patients was done to evaluate perioperative antibiotics in the prevention of postoperative infection of vascular access prostheses. Expanded polytetrafluoroethylene (PTFE) hemodialysis grafts were placed either in radiocephalic (19) or femorosaphenous
J R Turner et al.
Antimicrobial agents and chemotherapy, 12(1), 67-72 (1977-07-01)
By conventional laboratory evaluation procedures, the in vitro antibacterial activities of cefamandole and its O-formyl ester, cefamandole nafate, appear virtually identical. When the activities of these two compounds were examined for their ability to lyse log-phase cultures of susceptible bacteria
Adult linear IgA disease associated with an erythema multiforme-like drug reaction.
Z B Argenyi et al.
Cleveland Clinic journal of medicine, 54(5), 445-450 (1987-09-01)
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持