D0633
7-(2,3-二羟丙基)茶碱
PDE inhibitor, powder
别名:
喘定
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关于此项目
经验公式（希尔记法）:
C10H14N4O4
化学文摘社编号:
分子量:
254.24
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
41106305
EC Number:
207-526-1
MDL number:
Beilstein/REAXYS Number:
284563
Form:
powder
Quality level:
产品名称
7-(2,3-二羟丙基)茶碱,
form
powder
Quality Level
mp
161-162 °C (lit.)
SMILES string
CN1C(=O)N(C)c2ncn(CC(O)CO)c2C1=O
InChI
1S/C10H14N4O4/c1-12-8-7(9(17)13(2)10(12)18)14(5-11-8)3-6(16)4-15/h5-6,15-16H,3-4H2,1-2H3
InChI key
KSCFJBIXMNOVSH-UHFFFAOYSA-N
Gene Information
human ... PDE3A(5139), PDE4A(5141), PDE4B(5142), PDE4C(5143), PDE4D(5144)
Biochem/physiol Actions
7-(2,3-Dihydroxypropyl)theophylline is also called as dyphylline. Dyphylline serves as a bronchodilator and aids in better air flow through the lungs. It reduces the symptoms of chronic lung disorder such as asthma and bronchitis.
Features and Benefits
This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
存储类别
11 - Combustible Solids
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
S H Neau et al.
International journal of pharmaceutics, 179(1), 97-105 (1999-03-04)
Release data from ethylcellulose (EC) matrix tablets was analyzed to determine which release equation provides the best fit to the data and to observe the effect of drug solubility on the release mechanism(s). Tablets were prepared by direct compression of
Judyta Cielecka-Piontek et al.
Journal of pharmaceutical and biomedical analysis, 46(1), 52-57 (2007-10-16)
The following first-order rate constants of the degradation of ertapenem in INVANZ and meropenem in MERONEM were determined: (a) in dry air at 363, 373, 378, 383, 388, 393 K; (b) at increased relative air humidity (76.4% RH) at 313
Therapeutic Drug Monitoring and Toxicology by Liquid Chromatography (2017)
The AARP Guide to Pills: Essential Information on More Than 1,200 Prescription and Nonprescription Medicines, Including Generics, 302-302 (2006)
Mario Grassi et al.
International journal of pharmaceutics, 276(1-2), 107-114 (2004-04-29)
A mathematical model able to describe the release kinetics of two model drugs (Diprophylline and Theophylline) from partially coated hydroxypropylmethylcellulose (HPMC, Methocel) K4M) matrices is presented. As solvent interaction with the system and drug release can only take place in
商品
Cyclic nucleotides like cAMP modulate cell function via PKA activation and ion channels.
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| D0633-500G | 04061832897783 |
| D0633-1KG | 04061826744314 |
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