D0815
2-[4-(Dimethylamino)styryl]-1-ethylpyridinium iodide
≥99% purity (HPLC), solid
别名:
DASPEI
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关于此项目
经验公式（希尔记法）:
C17H21IN2
化学文摘社编号:
分子量:
380.27
NACRES:
NA.47
PubChem Substance ID:
UNSPSC Code:
12171500
EC Number:
223-248-3
MDL number:
Beilstein/REAXYS Number:
3783243
产品名称
2-[4-(Dimethylamino)styryl]-1-ethylpyridinium iodide, ≥99% (HPLC), solid
InChI
1S/C17H21N2.HI/c1-4-19-14-6-5-7-17(19)13-10-15-8-11-16(12-9-15)18(2)3;/h5-14H,4H2,1-3H3;1H/q+1;/p-1
SMILES string
[I-].CC[n+]1ccccc1\C=C\c2ccc(cc2)N(C)C
InChI key
AMAXNNVXIBDEMV-UHFFFAOYSA-M
assay
≥99% (HPLC)
form
solid
color
red
mp
267 °C (dec.) (lit.)
solubility
DMSO: 0.5 mg/mL, methanol: soluble
εmax
36.0-41.0 at 457-463 nm in methanol
application(s)
diagnostic assay manufacturing
hematology
histology
storage temp.
2-8°C
Quality Level
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Application
2-[4-(Dimethylamino)styryl]-1-ethylpyridinium iodide (DASPEI) has been used for the labelling of hair cells in larval zebrafish.
Biochem/physiol Actions
2-[4-(Dimethylamino)styryl]-1-ethylpyridinium iodide (DASPEI) accumulates in the mitochondria and has a large fluorescence Stokes shift. It is also used for the relative measurements of mitochondrial membrane potential.
Suitable as a mitochondrial stain in live cells.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Ru Zhang et al.
Biomolecules, 10(10) (2020-10-22)
Cochlear hair cells in human beings cannot regenerate after loss; however, those in fish and other lower species can. Recently, the role of inflammation in hair cell regeneration has been attracting the attention of scientists. In the present study, we
Development of a no-wash assay for mitochondrial membrane potential using the styryl dye DASPEI.
Jensen KH and Rekling JC
Journal of Biomolecular Screening, 15, 1071-1081 (2010)
Marina Yoffe et al.
Journal of experimental zoology. Part B, Molecular and developmental evolution, 334(7-8), 511-517 (2020-05-22)
The lateral line is the primary modality fish use to create a hydrodynamic image of their environment. These images contribute to a variety of behaviors, from rheotaxis to escape responses. Here we discern the contributions of visual and lateral line
W Armand Guiguemde et al.
Nature, 465(7296), 311-315 (2010-05-21)
Malaria caused by Plasmodium falciparum is a disease that is responsible for 880,000 deaths per year worldwide. Vaccine development has proved difficult and resistance has emerged for most antimalarial drugs. To discover new antimalarial chemotypes, we have used a phenotypic
Screen of FDA-approved drug library reveals compounds that protect hair cells from aminoglycosides and cisplatin.
Vlasits AL, et al.
Hearing Research, 294, 153-165 (2012)
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