D6288
6α,9α-Difluoroprednisolone 21-acetate 17-butyrate
≥98%
别名:
Difluprednate
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关于此项目
经验公式（希尔记法）:
C27H34F2O7
化学文摘社编号:
分子量:
508.55
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352202
EC Number:
245-815-4
MDL number:
sterility
non-sterile
Quality Level
assay
≥98%
form
powder
solubility
chloroform: 50 mg/mL, clear, colorless
shipped in
ambient
storage temp.
2-8°C
SMILES string
CCCC(=O)O[C@@]1(CC[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C)C(=O)COC(C)=O
InChI
1S/C27H34F2O7/c1-5-6-23(34)36-26(22(33)14-35-15(2)30)10-8-17-18-12-20(28)19-11-16(31)7-9-24(19,3)27(18,29)21(32)13-25(17,26)4/h7,9,11,17-18,20-21,32H,5-6,8,10,12-14H2,1-4H3/t17-,18-,20-,21-,24-,25-,26-,27-/m0/s1
InChI key
WYQPLTPSGFELIB-JTQPXKBDSA-N
Gene Information
human ... NR3C1(2908)
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
Eric J Sigler et al.
Retina (Philadelphia, Pa.), 34(2), 237-246 (2013-07-25)
To describe the clinical and histopathologic characteristics of inflammatory deposits occurring within intermediate duration postoperative perfluoro-n-octane (PFO) for inferior retinal detachment repair. Prospective interventional case series of consecutive patients with inferior retinal detachment treated with intermediate duration postoperative vitreous cavity
Shin-ichi Yasueda et al.
Journal of pharmaceutical and biomedical analysis, 30(6), 1735-1742 (2002-12-18)
A specific and sensitive method for the determination for difluprednate (DFBA) and its metabolite (deacetylated DFBA, DFB) in aqueous humor was developed. DFBA and DFB were initially absorbed on a Pinkerton-type column, then analyzed by high-performance liquid chromatography using a
Yixuan Dong et al.
Journal of pharmaceutical sciences, 108(6), 2002-2011 (2019-01-15)
Pharmaceutical emulsions contain multiple components, such as micellar, aqueous, and oil phases, leading to complex drug transfer and equilibrium phenomena. These complex components present challenges for the bioequivalence assessment of the drug products. The objective of the study was to
Atsuo Tanimoto et al.
Experimental dermatology, 27(1), 22-29 (2017-04-20)
Janus kinases (JAKs) are required for several inflammatory cytokine signalling pathways and are implicated in the pathogenesis of chronic dermatitis, including atopic dermatitis and psoriasis. JAK inhibitors are therefore promising therapeutic candidates for chronic dermatitis. In this study, we evaluated
Masazumi Yamaguchi et al.
International journal of pharmaceutics, 301(1-2), 121-128 (2005-07-19)
Preparation of oil-in-water (o/w) type lipid emulsion is one of the approaches to formulate drugs that are poorly water-soluble but can be dissolved in the oil phase of the emulsions. A synthetic glucocorticoid medicine, difluprednate (DFBA), is a water-insoluble compound.
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| D6288-50MG | 04061832856209 |
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