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Merck
CN

D8907

1,2-Dioctanoylethylene glycol

~99%

别名:

Ethylene glycol dioctanoate

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关于此项目

经验公式(希尔记法):
C18H34O4
化学文摘社编号:
分子量:
314.46
UNSPSC Code:
41106300
PubChem Substance ID:
MDL number:
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assay

~99%

form

liquid

storage temp.

−20°C

SMILES string

CCCCCCCC(=O)OCCOC(=O)CCCCCCC

InChI

1S/C18H34O4/c1-3-5-7-9-11-13-17(19)21-15-16-22-18(20)14-12-10-8-6-4-2/h3-16H2,1-2H3

InChI key

HTNFLUQQANUSLR-UHFFFAOYSA-N

Biochem/physiol Actions

Potent inhibitor of sn-1,2-diacylglycerol phosphorylation in vitro.


存储类别

12 - Non Combustible Liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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分析证书(COA)

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S Bourgoin et al.
The Journal of biological chemistry, 267(17), 11908-11916 (1992-06-15)
To determine the role of protein tyrosine phosphorylation in the activation of phospholipase D (PLD), electropermeabilized HL-60 cells labeled in [3H]alkyl-phosphatidylcholine were treated with vanadate derivatives. Micromolar concentrations of vanadyl hydroperoxide (V(4+)-OOH) induced accumulation of tyrosine-phosphorylated proteins. Concomitantly, V(4+)-OOH or
M Tóth
Biochimica et biophysica acta, 1210(1), 105-112 (1993-12-02)
Metabolic conversion of the synthetic DAG, dioctanoylglycerol (DOCG) into the dioctanoyl species of phosphatidic acid (PADOCG) and phosphatidylcholine (PCDOCG) in minced human primordial placenta incubated with [32P]phosphate was studied. Time-course experiments performed with 0.25 mM DOCG revealed a much higher
S E Severin et al.
FEBS letters, 232(2), 286-288 (1988-05-23)
Diol lipids (dioleoyl- and dioctanoylethylene glycol) at relatively low concentrations (approximately 10 microM) were found to activate significantly protein kinase C in the presence of phosphatidylserine or phosphatidylinositol. Since diol lipids are widespread minor lipid constituents of many cells [(1974)