E2127
β-雌二醇3-(β-D-葡萄糖醛酸) 钠盐
≥98% (HPLC), estradiol metbolite, powder
别名:
1,3,5(10)-Estratriene-3,17β-diol 3-glucuronide, 3,17β-Dihydroxy-1,3,5(10)-estratriene 3-glucuronide
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关于此项目
线性分子式:
C24H31O8Na
化学文摘社编号:
分子量:
470.49
UNSPSC Code:
51111800
PubChem Substance ID:
NACRES:
NA.77
MDL number:
产品名称
β-雌二醇3-(β-D-葡萄糖醛酸) 钠盐,
sterility
non-sterile
Quality Level
assay
≥98% (HPLC)
form
powder
solubility
water: 10 mg/mL, clear to slightly hazy
shipped in
ambient
storage temp.
−20°C
SMILES string
[Na].CC12CCC3C(CCc4cc(OC5OC(C(O)C(O)C5O)C(O)=O)ccc34)C1CCC2O
InChI
1S/C24H32O8.Na.H/c1-24-9-8-14-13-5-3-12(10-11(13)2-4-15(14)16(24)6-7-17(24)25)31-23-20(28)18(26)19(27)21(32-23)22(29)30;;/h3,5,10,14-21,23,25-28H,2,4,6-9H2,1H3,(H,29,30);;
InChI key
JKYLXXZHJUQLMK-UHFFFAOYSA-N
Application
β-Estradiol 3-(β-D-glucuronide) sodium salt has been used in estrogen administration. It has also been used to determine the amount of two types of glucuronidated estradiols such as estradiol-3- α glucuronide and estradiol-17- β glucuronide.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
涉药品监管产品
此项目有
Yuichiro Sato et al.
Xenobiotica; the fate of foreign compounds in biological systems, 42(9), 823-829 (2012-03-23)
The aims of this study were to quantify absolute protein levels of uridine 5'-diphosphate-glucuronosyltransferases (UGTs) 1A1 and 2B7 in human liver microsomes (HLMs) and to investigate their correlation with marker activities. A quantification method for UGT1A1 and UGT2B7 in HLMs
Linda B Tabas et al.
Analytical biochemistry, 310(1), 61-66 (2002-11-05)
This study investigated a high-throughput assay to measure multidrug resistance-associated protein (MRP1)-mediated uptake into membrane vesicles. Typically, a rapid filtration technique using a 12-filter vacuum manifold is used. We report here the development of a 96-well microtiter dish assay. MRP1-transfected
Direct, complex effects of estrogens on basal forebrain cholinergic neurons
Bora S H, et al.
Experimental Neurology, 194(2), 506-522 (2005)
Kathleen A O'Connor et al.
Journal of immunoassay & immunochemistry, 25(3), 259-278 (2004-10-06)
Our aim was to develop a statistical method to correct for non-parallelism in an estrone-3-glucuronide (E1G) enzyme immunoassay (EIA). Non-parallelism of serially diluted urine specimens with a calibration curve was demonstrated in an EIA for E1G. A linear mixed-effects analysis
Phillip M Gerk et al.
Drug metabolism and disposition: the biological fate of chemicals, 32(10), 1139-1145 (2004-07-29)
beta-estradiol 17-(beta-D-glucuronide) (E217G) is a well known cholestatic agent and substrate of multidrug resistance-associated protein 2 (Mrp2), whereas beta-estradiol 3-(beta-D-glucuronide) (E23G) is a noncholestatic regioisomer of E217G with unknown transport properties. The purpose of this study was to compare and
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| E2127-25MG | 04061832849812 |
| E2127-10MG | 04061833602447 |
| E2127-5MG | 04061833602454 |
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