E7138
乙琥胺
T-type calcium channel antagonist
别名:
2-乙基-2-甲基琥珀酰亚胺
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关于此项目
经验公式（希尔记法）:
C7H11NO2
化学文摘社编号:
分子量:
141.17
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352111
EC Number:
201-048-7
MDL number:
Quality level:
产品名称
乙琥胺,
Quality Level
solubility
ethanol: 100 mg/mL
SMILES string
O=C1NC(CC1(C)CC)=O
InChI
1S/C7H11NO2/c1-3-7(2)4-5(9)8-6(7)10/h3-4H2,1-2H3,(H,8,9,10)
InChI key
HAPOVYFOVVWLRS-UHFFFAOYSA-N
Gene Information
human ... CACNA1G(8913), CACNA1H(8912), CACNA1I(8911)
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相关类别
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Self-assembling PVA-F127 thermosensitive nanocarriers with highly sensitive magnetically-triggered drug release for epilepsy therapy in vivo
Huang HY, et al.
Journal of Materials Chemistry, 22(17), 8566-8573 (2012)
N Leresche et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 18(13), 4842-4853 (1998-06-23)
The action of ethosuximide (ETX) on Na+, K+, and Ca2+ currents and on tonic and burst-firing patterns was investigated in rat and cat thalamic neurons in vitro by using patch and sharp microelectrode recordings. In thalamocortical (TC) neurons of the
Behavioural responses of zebrafish larvae to acute ethosuximide exposure
Ji Y, et al.
Behavioural Pharmacology, 28(6), 428-440 (2017)
Tracy A Glauser et al.
Epilepsia, 54(1), 141-155 (2012-11-22)
Determine the optimal initial monotherapy for children with newly diagnosed childhood absence epilepsy (CAE) based on 12 months of double-blind therapy. A double-blind, randomized controlled clinical trial compared the efficacy, tolerability, and neuropsychological effects of ethosuximide, valproic acid, and lamotrigine
Emilio Russo et al.
Epilepsia, 52(7), 1341-1350 (2011-06-04)
Depression is most commonly associated with epilepsy. Recent reports have suggested a putative relationship between seizure development and onset of depressive behavior, whereas others proposed that two clinical entities might represent different neuropathologic aspects of the same neurologic disorder. The
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| E7138-100G | 04061832556475 |
| E7138-5G | 04061832556482 |
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