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Merck
CN

G7379

Guanidinosuccinic acid

别名:

N-Amidino-L-aspartic acid

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关于此项目

线性分子式:
C5H9O4N3
化学文摘社编号:
分子量:
175.14
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
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form

powder

color

white

storage temp.

2-8°C

SMILES string

NC(=N)NC(CC(O)=O)C(O)=O

InChI

1S/C5H9N3O4/c6-5(7)8-2(4(11)12)1-3(9)10/h2H,1H2,(H,9,10)(H,11,12)(H4,6,7,8)

InChI key

VVHOUVWJCQOYGG-UHFFFAOYSA-N

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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历史批次信息供参考:

分析证书(COA)

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A Torremans et al.
Brain research, 1008(1), 107-112 (2004-04-15)
Uremic retention solutes possibly contribute to neuronal hypoxia/ischemia and its consequences in patients with renal failure. We examined the in vitro effects of several uremic retention solutes on murine central neurons under chemically induced metabolic hypoxia by application of sodium
Youri E C Taes et al.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 23(4), 1330-1335 (2007-12-01)
Specific guanidino compounds have been described as uraemic toxins and their concentrations are increased in renal failure due to dimished glomerular filtration, whereas the guanidino compound creatine is used as a performance-enhancing substance in athletes. The present study investigates the
Michal Ciborowski et al.
PloS one, 7(2), e31982-e31982 (2012-03-03)
Abdominal aortic aneurysm (AAA) is a permanent and localized aortic dilation, defined as aortic diameter ≥3 cm. It is an asymptomatic but potentially fatal condition because progressive enlargement of the abdominal aorta is spontaneously evolving towards rupture.Biomarkers may help to
Burton D Cohen
Molecular and cellular biochemistry, 298(1-2), 195-198 (2006-12-01)
Guanidinosuccinic acid is an aberrant metabolite isolated 40 years ago in the blood and urine of uremic subjects and a suspect in the toxicity associated with renal failure. It plays a minor role in the bleeding diathesis of uremia, contributes
K Aoyagi et al.
Free radical research, 31(1), 59-65 (1999-09-17)
Guanidinosuccinic acid (GSA) is noted for its nitric oxide (NO) mimicking actions such as vasodilatation and activation of the N-methyl-D-aspartate (NMDA) receptor. We have reported that GSA is the product of argininosuccinate (ASA) and some reactive oxygen species, mainly the

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