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Merck
CN

G7379

Guanidinosuccinic acid

别名:

N-Amidino-L-aspartic acid

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线性分子式:
C5H9O4N3
化学文摘社编号:
分子量:
175.14
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
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form

powder

color

white

InChI

1S/C5H9N3O4/c6-5(7)8-2(4(11)12)1-3(9)10/h2H,1H2,(H,9,10)(H,11,12)(H4,6,7,8)

SMILES string

NC(=N)NC(CC(O)=O)C(O)=O

InChI key

VVHOUVWJCQOYGG-UHFFFAOYSA-N

storage temp.

2-8°C

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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历史批次信息供参考:

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Sunny Eloot et al.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 24(7), 2225-2232 (2009-02-20)
Patients with renal failure retain a large variety of uraemic solutes, characterized by different kinetic behaviour. It is not entirely clear what the impact is of increasing dialysis frequency and/or duration on removal efficiency, nor whether this impact is the
Madeline E Sherlock et al.
Biochemistry, 56(2), 352-358 (2016-12-22)
Recently, it was determined that representatives of the riboswitch candidates called ykkC and ykkC-III directly bind free guanidine. Guanidine-binding ykkC motif RNAs, now renamed guanidine-I riboswitches, were demonstrated to commonly regulate the expression of genes encoding guanidine carboxylases, as well
Burton D Cohen
Molecular and cellular biochemistry, 244(1-2), 31-36 (2003-04-19)
Guanidinosuccinic acid (GSA) is one of the earliest uremic toxins isolated and its toxicity identified. Its metabolic origins have remained obscure until recently when a series of studies showed that it arose from the oxidation of argininosuccinic acid (ASA) by
A Torremans et al.
Kidney international, 69(11), 2003-2012 (2006-04-28)
Polycystic kidney disease (PKD) accounts for 7-10% of all dialyzed renal insufficient patients. Accumulation of specific guanidino compounds (GCs) has been related to neurological, cardiovascular, hematological, and immunological complications of renal failure. In this study, we investigate whether the PKD/Mhm
Kazuharu Ienaga et al.
Biological & pharmaceutical bulletin, 32(7), 1204-1208 (2009-07-03)
The concentration of NZ-419 (5-hydroxy-1-methylimidazolidine-2,4-dione), an intrinsic antioxidant, has been shown to increase in the sera of animals and patients with chronic renal failure (CRF). This is the first report that orally administered exogenous NZ-419 prevents the initiation and/or progression

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