I8757
4-碘- L -苯丙氨酸
≥98.0% (TLC)
别名:
( S )-2-氨基-3-（4-碘苯基）丙酸
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关于此项目
经验公式（希尔记法）:
C9H10INO2
化学文摘社编号:
分子量:
291.09
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352209
MDL number:
Beilstein/REAXYS Number:
4411317
产品名称
4-碘- L -苯丙氨酸,
assay
≥98.0% (TLC)
Quality Level
form
powder
color
white to off-white
storage temp.
−20°C
SMILES string
N[C@@H](Cc1ccc(I)cc1)C(O)=O
InChI
1S/C9H10INO2/c10-7-3-1-6(2-4-7)5-8(11)9(12)13/h1-4,8H,5,11H2,(H,12,13)/t8-/m0/s1
InChI key
PZNQZSRPDOEBMS-QMMMGPOBSA-N
Biochem/physiol Actions
4-碘-L-苯丙氨酸可作为模型非天然 α通过蛋白石 (UGA) 密码子改变主要氨基酸组成的氨基酸。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
D Hellwig et al.
Nuklearmedizin. Nuclear medicine, 47(5), 220-224 (2008-10-15)
Recently, p-[(123)I]iodo-L-phenylalanine (IPA) was clinically validated for brain tumour imaging. Preclinical studies demonstrated uptake of IPA into pancreatic adenocarcinoma suggesting its diagnostic application in patients with pancreatic tumours. The aim was to study the tumour uptake of IPA in patients
Samuel Samnick et al.
European journal of nuclear medicine and molecular imaging, 31(4), 532-541 (2004-01-15)
Pancreatic cancer is associated with the worst 5-year survival rate of any human cancer. This high mortality is due, in part, to difficulties in establishing early and accurate diagnosis. Because most tumours share the ability to accumulate amino acids more
D R Harding et al.
International journal of peptide and protein research, 26(2), 208-213 (1985-08-01)
The amino terminal fragment (1-15) of apolipoprotein C-1, H-Thr-Pro-Asp-Val-Ser-Ser-Ala-Leu-Asp-Lys-Leu-Lys-Glu-Phe14-Gly was prepared by the solid phase method. However, the phenylalanine residue at position 14 was replaced with p-iodophenylalanine in the chemical synthesis. The preparation of t-butyloxy-carbonyl-p-iodophenylalanine is described. After completion of
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| I8757-1G | 04061826059890 |