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Merck
CN

K2126

β-Estradiol-6-one 6-(O-carboxymethyloxime)

≥98.00% (TLC), powder

别名:

β-Estradiol-6-(O-carboxymethyl)oxime, 1,3,5(10)-Estratriene-3,17β-diol-6-one6-(O-carboxymethyloxime), 3,17β-Dihydroxy-1,3,5(10)-estratriene 6-(O-carboxymethyl)oxime, 6-Ketoestradiol 6-(O-carboxymethyloxime)

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关于此项目

经验公式(希尔记法):
C20H25NO5
化学文摘社编号:
分子量:
359.42
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
51111800
MDL number:
Beilstein/REAXYS Number:
2484202
Assay:
≥98.00% (TLC)
Form:
powder
Quality level:
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产品名称

β-Estradiol-6-one 6-(O-carboxymethyloxime),

biological source

synthetic (organic)

Quality Level

assay

≥98.00% (TLC)

form

powder

solubility

ethanol: 19.60-20.40 mg/mL, clear, colorless to faintly yellow

shipped in

ambient

storage temp.

2-8°C

SMILES string

C[C@]12CC[C@H]3[C@@H](C\C(=N\OCC(O)=O)c4cc(O)ccc34)[C@@H]1CC[C@@H]2O

InChI

1S/C20H25NO5/c1-20-7-6-13-12-3-2-11(22)8-15(12)17(21-26-10-19(24)25)9-14(13)16(20)4-5-18(20)23/h2-3,8,13-14,16,18,22-23H,4-7,9-10H2,1H3,(H,24,25)/b21-17-/t13-,14-,16+,18+,20+/m1/s1

InChI key

AWARIMYXKAIIGO-UYGYUSPXSA-N

General description

β-Estradiol-6-one 6-(O-carboxymethyloxime) is a derivative of 17β-estradiol.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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M Malawer et al.
Journal of surgical oncology, 25(3), 148-152 (1984-03-01)
Hormonal receptors of giant cell tumors (GCTs) have not been previously reported. Five cases of GCT of bone were analyzed for estrogen and progesterone binding. Frozen sections were studied by a histochemical method, using 17-beta-6-CMOBSA-FITC and 11-alpha-hydroxyprogesterone-HS-BSA-TMRITC. Cytoplasmic fluorescence with
C J Meijer et al.
Virchows Archiv. B, Cell pathology including molecular pathology, 40(1), 27-37 (1982-01-01)
The present study defines criteria for determining the presence of estrogen-receptors in human breast carcinomas demonstrated by a histochemical assay using 17 beta-estradiol-carboxy-methyl-oxim-bovine serum albumen-FITC. The criteria were: 1) the percentage of cells showing fluorescence; 2) the intensity of the
Markus Lacorn et al.
Journal of immunological methods, 297(1-2), 225-236 (2005-03-22)
17beta-estradiol (E2) concentrations are in the low pg/ml range in plasma. To develop a sensitive enzyme immunoassay (EIA) for E2-determination a highly specific antibody raised against a 6-carboxymethyl (CMO)-E2-bovine serum albumine conjugate was used. Based on 6-CMO-E2 and 6-amino-E2, four
May L Chiu et al.
Biotechnology and applied biochemistry, 58(1), 75-82 (2011-03-31)
A convenient homogeneous enzyme immunoassay for estradiol is described. Unlike heterogeneous immunoassays, which require time-consuming separation steps or expensive automated systems, homogeneous immunoassays, wherein all reagents are freely suspended in bulk solution, can be simple and fast without costly instrumentation.
Mingzhe Liu et al.
Journal of bioscience and bioengineering, 111(5), 564-568 (2011-02-01)
Antibodies were covalently conjugated with poly(ethylene glycol) (PEG) and the properties of the PEGylated antibodies in organic media were investigated. Two types of monoclonal antibody were used in this study. One was a monoclonal antibody (abzyme) that was prepared against

全球贸易项目编号

货号GTIN
K2126-5MG04061832856698
K2126-50MG04061832856681

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