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Merck
CN

M1380

N6-单丁酰腺苷3′:5′-环单磷酸盐 钠盐

别名:

6MB-cAMP

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关于此项目

经验公式(希尔记法):
C14H17N5NaO7P
化学文摘社编号:
分子量:
421.28
NACRES:
NA.51
PubChem Substance ID:
UNSPSC Code:
41106305
MDL number:
Assay:
≥97.5% (HPLC)
Biological source:
synthetic (organic)
Form:
powder or crystals
Solubility:
water: 50 mg/mL, clear, colorless
Storage temp.:
−20°C
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biological source

synthetic (organic)

assay

≥97.5% (HPLC)

form

powder or crystals

solubility

water: 50 mg/mL, clear, colorless

storage temp.

−20°C

SMILES string

[Na].CCCC(=O)Nc1ncnc2n(cnc12)C3OC4COP(O)(=O)OC4C3O

InChI

1S/C14H18N5O7P.Na.H/c1-2-3-8(20)18-12-9-13(16-5-15-12)19(6-17-9)14-10(21)11-7(25-14)4-24-27(22,23)26-11;;/h5-7,10-11,14,21H,2-4H2,1H3,(H,22,23)(H,15,16,18,20);;

InChI key

RHNOUOJKQVKESB-UHFFFAOYSA-N

Application

N6-单丁基腺苷3′:5′-环单磷酸钠盐适用于
  • 验证其刺激节后反应长效增强作用的假说
  • 作为蛋白激酶A激活剂,在人原代培养的甲状腺细胞中分析cAMP级联调控基因表达的调节
  • 分析其对假孕兔黄体孕酮产生的影响

Biochem/physiol Actions

激活蛋白激酶A的cAMP的膜透性类似物,对磷酸二酯酶降解耐受


存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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T T Puck et al.
Somatic cell and molecular genetics, 17(5), 489-503 (1991-09-01)
Genome exposure studies were carried out on malignant CHO-K1 and C6 rat glioma cells and their respective, phenotypically normal counterparts (reverse-transformed CHO-K1, and both reverse-transformed C6 glioma and normal rat fibroblasts). Cells were subjected to the nick-translation technique previously developed
G De Pergola et al.
Acta endocrinologica, 123(1), 61-66 (1990-07-01)
The effects of testosterone treatment (2 mg every 14 days, for three months) on adipocyte lipolysis of intact (250-300 g body weight) and ovariectomized female rats were studied. Testosterone treatment of intact rats had no effect. Ovariectomy was followed by
Ketty Bacallao et al.
PloS one, 8(12), e82354-e82354 (2013-12-19)
In Schwann cells (SCs), cyclic adenosine monophosphate (cAMP) not only induces differentiation into a myelinating SC-related phenotype, but also synergistically enhances the mitogenic action of growth factors such as neuregulin. To better understand the molecular mechanism by which cAMP exerts



全球贸易项目编号

货号GTIN
M1380-100MG04061833007624
M1380-25MG04061833007631