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Merck
CN

M4016

甲基磺酸甲酯

~99% (GC)

别名:

甲磺酸甲酯

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关于此项目

线性分子式:
CH3SO3CH3
化学文摘社编号:
分子量:
110.13
EC Number:
200-625-0
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
1098586
MDL number:
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assay

~99% (GC)

refractive index

n20/D 1.414 (lit.)

bp

202-203 °C (lit.)

density

1.3 g/mL at 25 °C (lit.)

SMILES string

COS(C)(=O)=O

InChI

1S/C2H6O3S/c1-5-6(2,3)4/h1-2H3

InChI key

MBABOKRGFJTBAE-UHFFFAOYSA-N

Biochem/physiol Actions

DNA 加合物;优先地将甲基加合到 DNA 的 7-鸟嘌呤,也可加合到 3-腺嘌呤和 3-鸟嘌呤。

Other Notes

This product has been replaced by 129925-ALDRICH | Methyl methanesulfonate 99%


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signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Chronic 2 - Carc. 2 - Eye Irrit. 2 - Muta. 1B - Repr. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT RE 2 Inhalation

target_organs

Lungs

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

219.2 °F - closed cup

flash_point_c

104 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

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Cathrine Broberg Vågbø et al.
DNA repair, 12(3), 188-195 (2013-01-02)
Cytotoxic 1-methyladenine (1-meA) and 3-methylcytosine (3-meC) lesions induced in DNA and RNA in vitro and in pre-damaged DNA and RNA bacteriophages in vivo are repaired by the Escherichia coli (E. coli) protein AlkB and a human homolog, ALKBH3. However, it
Stephen Godin et al.
Nucleic acids research, 41(8), 4525-4534 (2013-03-06)
The Saccharomyces cerevisiae Shu complex, consisting of Shu1, Shu2, Csm2 and Psy3, promotes error-free homologous recombination (HR) by an unknown mechanism. Recent structural analysis of two Shu proteins, Csm2 and Psy3, has revealed that these proteins are Rad51 paralogues and
Dongqing Huang et al.
Molecular and cellular biology, 33(8), 1515-1527 (2013-02-06)
Cells employ error-free or error-prone postreplication repair (PRR) processes to tolerate DNA damage. Here, we present a genome-wide screen for sensitivity to 0.001% methyl methanesulfonate (MMS). This relatively low dose is of particular interest because wild-type cells exhibit no discernible