M6524
盐酸甲氧明 盐酸盐
α1-adrenoceptor agonist
别名:
α-(1--氨基乙基)-2,5-二甲氧基苄醇 盐酸盐
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关于此项目
经验公式（希尔记法）:
C11H17NO3 · HCl
化学文摘社编号:
分子量:
247.72
EC 号:
MDL编号:
UNSPSC代码:
12352116
PubChem化学物质编号:
NACRES:
NA.77
产品名称
盐酸甲氧明 盐酸盐,
储存温度
2-8°C
SMILES字符串
Cl[H].COc1ccc(OC)c(c1)C(O)C(C)N
InChI
1S/C11H17NO3.ClH/c1-7(12)11(13)9-6-8(14-2)4-5-10(9)15-3;/h4-7,11,13H,12H2,1-3H3;1H
InChI key
YGRFXPCHZBRUKP-UHFFFAOYSA-N
基因信息
human ... ADRA1A(148), ADRA1B(147), ADRA1D(146)
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相关类别
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
R H Lee et al.
Journal of neurophysiology, 81(5), 2164-2174 (1999-05-13)
Enhancement of bistability in spinal motoneurons in vivo by the noradrenergic alpha1 agonist methoxamine. Like many types of motoneurons, spinal motoneurons in the adult mammal can exhibit bistable behavior. This means that short periods of excitatory input can initiate long
Alain Frigon et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 31(15), 5579-5588 (2011-04-15)
Extra forces or torques are defined as forces or torques that are larger than would be expected from the input or stimuli, which can be mediated by properties intrinsic to motoneurons and/or to the muscle. The purpose of this study
Lindsay D MacKenzie et al.
The journal of sexual medicine, 8(9), 2461-2471 (2011-06-29)
Mean arterial pressure (MAP) and specific regulation of penile blood flow are the primary determinants of an erection. While this concept is well recognized, the differential relationship between systemically acting vasoactive factors on arterial pressure and erectile responses is not
Jiun-Jr Wang et al.
The Canadian journal of cardiology, 29(2), 243-253 (2012-05-25)
Using the reservoir-wave approach, we studied wave propagation, reflection, and re-reflection in the canine aorta with administrations of sodium nitroprusside (NP) and methoxamine (Mtx). In 8 anaesthetized dogs, excess pressures were calculated from pressure and flow measurements at 4 locations
Robert H Thiele et al.
Anesthesia and analgesia, 113(2), 284-296 (2011-04-27)
Phenylephrine and methoxamine are direct-acting, predominantly α(1) adrenergic receptor (AR) agonists. To better understand their physiologic effects, we screened 463 articles on the basis of PubMed searches of "methoxamine" and "phenylephrine" (limited to human, randomized studies published in English), as
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Review alpha 1 adrenoceptors as well as their agonists, antagonists, and tissue expression patterns. We suggest several modulators and alternatives for working with a-1 adrenoreceptors.
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