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M6532

(+)-氯化毒蕈碱

Name: (+)-氯化毒蕈碱
Brand: SIGMA

~95% (TLC), Muscarinic acethylcholine receptor agonist, powder

别名:

(+)-(2S,4R,5S)-Tetrahydro-4-hydroxy-N,N,N,5-tetramethyl-2-furanmethanammonium chloride, (+)-Tetrahydro-4β-hydroxy-N,N,N,5α-tetramethyl-2α-furanmethanaminium chloride

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关于此项目

经验公式（希尔记法）:

C₉H₂₀ClNO₂

化学文摘社编号:

2303-35-7

分子量:

209.71

NACRES:

NA.77

PubChem Substance ID:

24897094

UNSPSC Code:

12352200

EC Number:

218-963-2

MDL number:

MFCD00069312

Assay:

~95% (TLC)

Form:

powder

Quality level:

200

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属性

产品名称

(+)-氯化毒蕈碱, ~95% (TLC), powder

assay

~95% (TLC)

Quality Level

200

form

powder

color

white

solubility

H₂O: 50 mg/mL

SMILES string

[Cl-].C[C@@H]1O[C@@H](C[C@H]1O)C[N+](C)(C)C

InChI

1S/C9H20NO2.ClH/c1-7-9(11)5-8(12-7)6-10(2,3)4;/h7-9,11H,5-6H2,1-4H3;1H/q+1;/p-1/t7-,8-,9+;/m0./s1

InChI key

WUFRNEJYZWHXLC-CTERPIQNSA-M

说明

Biochem/physiol Actions

Prototype muscarinic acetylcholine receptor agonist; active enantiomer.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Acetylcholine Receptors (Muscarinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Disclaimer

极易吸湿

pictograms

GHS06

signalword

Danger

hcodes

H300 + H310 + H330

pcodes

P260 - P262 - P264 - P280 - P302 + P352 + P310 - P304 + P340 + P310

Hazard Classifications

Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral

存储类别

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

0000276229

0000276228

118K3797

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商品

DISCOVER Bioactive Small Molecules for Neuroscience

Muscarine modulates Ca2+ channel currents in rat sensorimotor pyramidal cells via two distinct pathways.

A E Stewart et al.

Journal of neurophysiology, 81(1), 72-84 (1999-01-23)

We used the whole cell patch-clamp technique and single-cell reverse transcription-polymerase chain reaction (RT-PCR) to study the muscarinic receptor-mediated modulation of calcium channel currents in both acutely isolated and cultured pyramidal neurons from rat sensorimotor cortex. Single-cell RT-PCR profiling for

Cholinergic axons regulate type I acini in salivary glands of Ixodes ricinus and Ixodes scapularis ticks.

Lourdes Mateos-Hernandéz et al.

Scientific reports, 10(1), 16054-16054 (2020-10-01)

Regulatory factors controlling tick salivary glands (SGs) are direct upstream neural signaling pathways arising from the tick's central nervous system. Here we investigated the cholinergic signaling pathway in the SG of two hard tick species. We reconstructed the organization of

Presynaptic effects of muscarine on ACh release at the frog neuromuscular junction.

I Slutsky et al.

The Journal of physiology, 514 ( Pt 3), 769-782 (1999-01-12)

1. Presynaptic effects of muscarine on neurotransmitter release were studied at the frog neuromuscular junction, using focal depolarization of the presynaptic terminal to different levels. 2. Muscarine (10 microM) had a dual effect on ACh release: concomitant inhibition and enhancement

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M6532-5MG	04061834061014
M6532-10MG	04061832092126