usage
sufficient for 100 fluorometric tests
application(s)
pharmaceutical
detection method
fluorometric
relevant disease(s)
cardiovascular diseases
storage temp.
−20°C
Gene Information
human ... LCAT(3931)
General description
血浆蛋白卵磷脂胆固醇酰基转移酶（LCAT）可催化酰基从磷脂酰胆碱的sn2位转移到胆固醇的3-羟基，从而生成胆固醇酯。这种酶活性发生在高密度脂蛋白（HDL）的表面。由LCAT生成的胆固醇酯可以填充到HDL的核心。
Application
LCAT活性测定试剂盒用于测定血浆样品中的卵磷脂胆固醇酰基转移酶活性。
该方法的应用包括高通量筛选、作用机制研究和构效关系（SAR）研究。
适用于测定血浆或血清中LCAT的磷脂酶活性。
Biochem/physiol Actions
LCAT活性检测试剂盒 是用于测定LCAT（卵磷脂胆固醇酰基转移酶）磷脂酶活性的荧光检测法(λEx=390 nm/λEm=470 nm)。该测定可以通过用碘乙酸盐或另一种光谱上良性（非Ellman′s试剂）LCAT抑制剂抑制LCAT进行验证。
Features and Benefits
兼容高通量操作系统。
Analysis Note
仅试剂盒组分
产品编号
说明
- Substrate Reagent .1 mL
- READ Reagent 30 mL
- LCAT Assay Buffer 20 mL
signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
存储类别
3 - Flammable liquids
flash_point_f
49.5 °F
flash_point_c
9.7 °C
法规信息
危险化学品
此项目有
相关内容
Instructions
Carey J Ng et al.
Arteriosclerosis, thrombosis, and vascular biology, 27(6), 1368-1374 (2007-04-21)
We have previously reported that human paraoxonase 3 (PON3) is an HDL-associated protein capable of preventing LDL oxidation in vitro. The objective of the present study was to determine whether elevated levels of human PON3 in mice could protect against
Agnieszka Kuchta et al.
International journal of molecular sciences, 20(5) (2019-03-13)
In chronic kidney disease (CKD), the level of high-density lipoprotein (HDL) decreases markedly, but there is no strong inverse relationship between HDL-cholesterol (HDL-C) and cardiovascular diseases. This indicates that not only the HDL-C level, but also the other quantitative changes
Mitigating efficacy of piperine in the physiological derangements of high fat diet induced obesity in Sprague Dawley rats.
BrahmaNaidu P, et al.
Chemico-Biological Interactions, 221, 42-51 (2014)
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| MAK107-1KT | 04061834065326 |